Generation of a Molecular Imprinted Membrane by Coating Cellulose Acetate onto a ZrO₂-Modified Alumina Membrane for the Chiral Separation of Mandelic Acid Enantiomers

Abstract

An alumina template modified with ZrO2 was coated with cellulose acetate (CA) containing imprinted molecules for a novel enantioselective membrane. The preparation, morphologies, and properties of the different membranes were introduced and investigated. The morphologies of the membranes were examined using a scanning electron microscope. The best performing CA amount in the casting solution was observed to be 15 wt %, and this was chosen as the preparation amount for the resulting membrane. (S)-(+)-Mandelic acid was used as imprinted molecules to prepare the molecular imprinted nanochannel membrane, which enhanced the permselectivity and flux compared with the traditional membrane, and the separation factor was as high as 35. And this membrane has the best separation effect on (R,S)-mandelic acid when compared with (R,S)-malic acid and (R,S)-lactic acid.

A Comprehensive Review on Polymeric Nano-Composite Membranes for Water Treatment

“…Zakeritabar et al [134] fabricated PSf membrane incorporated with zirconium dioxide (ZrO 2 ) and tin dioxide (SnO 2 ) via sol-gel method which showed enhanced water flux, good hydrophilicity, high photocatalytic activity and improved antifouling behavior. Li et al [136] coated cellulose acetate with ZrO 2 modified with alumina template for fabrication of enantioselective membrane for separating chiral enantiomers of madelic acid. Best performance was obtained with addition of 15% cellulose acetate in casting solution along with increased flux, permselectivity and high separation factor (35) as compared to traditional membrane.…”

Chiral Recognition for Chromatography and Membrane-Based Separations: Recent Developments and Future Prospects

“…Finally, the solvent was completely evaporated on a glass plate under a vacuum at 100 °C to prepare an MMA-NIPAm chiral separation membrane that effectively separated racemic equol. In another study [ 152 ], alumina templates coated with cellulose acetate (CA) were used for the analysis and preparation of various membranes. The optimal amount of CA added to the casting solution was investigated.…”

Preparation and High Performance of Cellulose Acetate Films by Grafting with Imidazole Ionic Liquid

“…Polymeric films have some applicable advantages, such as good film forming ability, low cost of raw materials, environmental resistance, and simple operation. , In this case, a variety of materials have been used for gas separation films in the past few decades. Among these films, polymeric films have been applied in industrial gas separations for decades, − the main ones being polyimide (PI), poly­(vinylidene fluoride) (PVDF), poly­(dimethyl siloxane) (PDMS), polysulfone (PSF), polyetherimide (PEI), and cellulose derivatives. , In addition to the advantages of polymeric films, these films have an inevitable limitation in the field of gas separation applications, which is called the tradeoff of permeability and selectivity. , Nonetheless, polymeric films are still good candidates for gas separation, but more points of view are necessary to enhance the gas permselectivity above the tradeoff …”