Generation of microfluidic flow using an optically assembled and magnetically driven microrotor

Köhler, Jannis; Ghadiri, Reza; Ksouri, Sarah Isabelle; Guo, Qingchuan; Gurevich, Evgeny L.; Ostendorf, Andreas

doi:10.1088/0022-3727/47/50/505501

Cited by 15 publications

(16 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Owing to the aforementioned merits, magnetic field directed manipulation has found wide applications in cutting-edge biomedical research, e.g. , microfluidic mixing, 57,58 winding DNA/RNA strands and probing their torsional stiffness. 59–65 …”

Section: Physical-field-driven Rotary Nanomotorsmentioning

confidence: 99%

See 1 more Smart Citation

Man-made rotary nanomotors: a review of recent developments

et al. 2016

View full text Add to dashboard Cite

The development rotary nanomotors is an essential step towards intelligent nanomachines and nanorobots. In this article, we review the concept, design, working mechanisms, and applications of the state-of-the-art rotary nanomotors made from synthetic nanoentities. The rotary nanomotors are categorized according to the energy sources employed to drive the rotary motion, including biochemical, optical, magnetic, and electric fields. The unique advantages and limitations for each type of rotary nanomachines are discussed. The advances of rotary nanomotors is pivotal for realizing dream nanomachines for myriad applications including microfluidics, biodiagnosis, nano-surgery, and biosubstance delivery.

show abstract

Section: Physical-field-driven Rotary Nanomotorsmentioning

confidence: 99%

“…58 Three polystyrene microspheres were assembled as a rotor via manipulation with optical tweezers and strategical conjugation with Streptavidin-Biotin reactions. The polystyrene sphere in the center was functionalized with Streptavidin and the other two spheres were coated with magnetite and Biotin.…”

Section: Physical-field-driven Rotary Nanomotorsmentioning

confidence: 99%

Man-made rotary nanomotors: a review of recent developments

et al. 2016

View full text Add to dashboard Cite

show abstract

“…The authors later adopted this method to develop a user‐configured microenvironment for studying cellular development processes (Figure b) . Additionally, another optical assembled microrotor was proposed by Köhler et al recently, and it was actuated by magnetic field as a micropump . Other optical manipulating techniques rather than optical tweezer have been investigated as well in the past.…”

Section: Applications Of Remotely Controllable Micromachines Fabricatmentioning

confidence: 99%

Microstructures Fabricated by Two‐Photon Polymerization and Their Remote Manipulation Techniques: Toward 3D Printing of Micromachines

Lin

2018

Advanced Optical Materials

View full text Add to dashboard Cite

As a promising microfabrication method, two-photon polymerization (TPP) underwent a rapid development for various applications in chemistry, biology, pharmaceuticals, microfluidics, and so forth. In recent years, the method has received particular attention because of its application for micromachines, including those requiring remote manipulation. Different manipulating techniques such as magnetic, optic, and acoustic manipulation are realized on TPP-fabricated microstructures, demonstrating the great potential for further development of micromachines. Nonetheless, most of the work is still at early stages, only proofing conceptual ideas. For instance, magnetically driven microswimmers are only investigated in artificial experimental environments, and it is still challenging to tackle complex in vivo conditions. Although a long journey is still ahead for using these micromachines in daily life, it is predictable that the combination of two-photon polymerization associated with remotely driven techniques will benefit various fields. Remotely Driven Micromachines

show abstract

“…The rotational motion of microstructures in microchannels can be used to mix different liquid samples or induce directed flow 30 . In the following paragraphs, the optical assembly technique presented is applied to such a microfluidic application.…”

Section: Micro-rotor Assembly and Actuationmentioning

confidence: 99%

Optical screw-wrench for microassembly

et al. 2017

View full text Add to dashboard Cite

For future micro-and nanotechnologies, the manufacturing of miniaturized, functionalized, and integrated devices is indispensable. In this paper, an assembly technique based on a bottom-up strategy that enables the manufacturing of complex microsystems using only optical methods is presented. A screw connection is transferred to the micrometer range and used to assemble screwand nut-shaped microcomponents. Micro-stereolithography is performed by means of two-photon polymerization, and microstructures are fabricated and subsequently trapped, moved, and screwed together using optical forces in a holographic optical tweezer set-up. The design and construction of interlocking microcomponents and the verification of a stable and releasable joint form the main focus of this paper. The assembly technique is also applied to a microfluidic system to enable the pumping or intermixing of fluids on a microfluidic chip. This strategy not only enables the assembly of microcomponents but also the combination of different materials and features to form complex hybrid microsystems.

show abstract

Generation of microfluidic flow using an optically assembled and magnetically driven microrotor

Cited by 15 publications

References 27 publications

Man-made rotary nanomotors: a review of recent developments

Man-made rotary nanomotors: a review of recent developments

Microstructures Fabricated by Two‐Photon Polymerization and Their Remote Manipulation Techniques: Toward 3D Printing of Micromachines

Optical screw-wrench for microassembly

Contact Info

Product

Resources

About