2021
DOI: 10.3390/v13040545
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Genetic Diversity of Enteric Viruses in Children under Five Years Old in Gabon

Abstract: Enteric viruses are the leading cause of diarrhea in children globally. Identifying viral agents and understanding their genetic diversity could help to develop effective preventive measures. This study aimed to determine the detection rate and genetic diversity of four enteric viruses in Gabonese children aged below five years. Stool samples from children <5 years with (n = 177) and without (n = 67) diarrhea were collected from April 2018 to November 2019. Norovirus, astrovirus, sapovirus, and aichivirus A… Show more

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Cited by 12 publications
(13 citation statements)
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“…Acute gastroenteritis (AGE) is one of the leading causes of mortality and morbidity among infants and children worldwide. Annually, 700 million cases of gastroenteritis are reported worldwide, resulting in 0.8–2 million deaths, 1 making it the second leading cause of death among infants and children under 5 years of age 2 . Various pathogens including bacteria, viruses, protozoa and helminths can cause this disease 3 .…”
Section: Introductionmentioning
confidence: 99%
“…Acute gastroenteritis (AGE) is one of the leading causes of mortality and morbidity among infants and children worldwide. Annually, 700 million cases of gastroenteritis are reported worldwide, resulting in 0.8–2 million deaths, 1 making it the second leading cause of death among infants and children under 5 years of age 2 . Various pathogens including bacteria, viruses, protozoa and helminths can cause this disease 3 .…”
Section: Introductionmentioning
confidence: 99%
“…The lack of exclusion of adenovirus as an aetiological agent of gastroenteritis is a limitation of this study. In addition, of the 38 asymptomatic cases of RVA gastroenteritis, eleven were also positive for noroviruses, astroviruses or sapoviruses [26]. Therefore, we cannot exclude the possibility that other pathogens could be responsible for the patients' symptoms in this study.…”
Section: Discussionmentioning
confidence: 79%
“…1 ). RVA was diagnosed in 112 of them (98/177 with diarrhoea and 14/67 without diarrhoea) [ 16 , 17 ].
Fig.
…”
Section: Methodsmentioning
confidence: 99%
“…
Fig. 1 Flow chart on investigated study population [ 17 ]; RVA -rotavirus A; RT-qPCR - Quantitative reverse transcription polymerase chain reaction.
…”
Section: Methodsmentioning
confidence: 99%