Taking into account the better agro-ecological adaptations developed over time to climate changed conditions, cereal local populations (landraces) represent a valuable plant genetic resources with their perspective reflected in the creation of better quality commercial cereal genotypes. The objectives of this research were to explore: i) the genetic variability of nutritional properties of Macedonian landraces of small grain cereals-wheat, barley, oat, and rye; ii) associations among nutritional properties; iii) strength and weakness of landraces based on nutritional properties profiles. Collecting missions were carried out in 2013 year in different locations of rural areas at the territory of Republic of Macedonia. Ten sub-samples of 100 g seeds were extracted from each of regenerated landrace in order to obtain a well-balanced analytical sample. All samples were analysed for moisture content-MOI (%), protein content-PC (%), fat content-FC (%), crude fibre content-CF (%), wet gluten content-WG (%), and dry gluten content-DG (%). In regard to assessed nutritional properties the most perspective landraces proved to be: Okalesta bela (CF of = 2.62%) of bread wheat; Zimski (WG of = 9.24%), Dabilski nizok (DG of =