Genetic Polymorphism of Cytokines as a Predictor of Phenotypic Development of Chronic Pain Syndrome in Cancer Patients

Abstract

The authors present a literature review using materials provided in the following databases: "MedLine", "PubMed", "Wiley Online Library", "Web of Science", "Oxford University Press", "SAGE Premier", dated 1995-2016. The paper describes the results of current international studies on the role of cytokine genes polymorphisms in the genesis of chronic cancer pain. We emphasize the role of inter-individual differences based on genetic polymorphism of cytokines and their receptors in personalized anesthetic care and accompanying therapy in oncology. (International Journal of Biomedicine. 2017;7(4):277-281.)