Gestational Diabetes Mellitus Is a Significant Risk Factor for Long-Term Maternal Renal Disease

Abstract

GDM is a significant risk factor for future maternal renal morbidity. The risk is more substantial for patients with recurrent episodes of GDM.

FIGO (International Federation of Gynecology and Obstetrics) Postpregnancy Initiative: Long‐term Maternal Implications of Pregnancy Complications—Follow‐up Considerations

“…In addition to type 2 diabetes, it should also be recognized that women who are diagnosed with GDM have elevated risks of other major medical conditions, including advanced liver disease, chronic kidney disease, ophthalmic morbidity in general and retinopathy in particular, female malignancies and, most importantly, CVD . Of note, the risks of serious liver disease, end‐stage kidney disease, and severe ophthalmologic outcomes appear to be dependent on the intercurrent development of type 2 diabetes in this patient population .…”

Preconception management of women with obesity: A systematic review

“…Of women with gestational diabetes, 70% will develop type 2 diabetes within the subsequent decade . Women with obesity who develop gestational diabetes have a significantly increased long‐term risk of renal disease and left ventricular dysfunction compared with normal weight women who develop gestational diabetes.…”

Gestational diabetes: An overview with attention for developing countries

“…Short-term, they may show high stress level, low sleep quality, and impaired cognitive functions (Hayase et al 2014;Keskin et al 2015). Moreover, they can develop thyroiditis, renal diseases, and type 2 DM (Beharier et al 2015;Hopmans et al 2015;Maleki and Tavosi 2015). Long-term eff ects, instead, are subclinical atherosclerosis, arterial hypertension, and cardiovascular disease (CVD) (Li et al 2014;Oliveira et al 2015).…”