Giant Aortic Thrombus in the Ascending Aorta and Perforation of Bowel Associated With Cocaine Use

Poon, Shi Sum; Nawaytou, Omar; Hing, Alfred; Field, Mark

doi:10.1016/j.athoracsur.2017.03.033

Cited by 10 publications

(9 citation statements)

References 6 publications

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“…We performed a literature search in PubMed and Scopus up to March 20, 2022, using the combination of the following keywords: “Aorta” OR “Aortic” and “Thrombosis” OR “Thrombus” and “Cocaine.” We found seven reported cases of aortic thrombus due to cocaine use [ 3 – 8 ], and their baseline characteristics are presented in Table 1 . Six of the seven patients were cocaine users, while the 7th patient was exposed to cocaine in utero.…”

Section: Resultsmentioning

confidence: 99%

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Floating aortic arch thrombus involving the left common carotid artery complicated with ischemic stroke associated with cocaine use

et al. 2022

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Background Floating aortic thrombi (FLOAT) are rare, with very few cases attributed to cocaine use. We report a new case of FLOAT involving the left common carotid artery due to cocaine use, for the first time, complicated with acute ischemic stroke. Methods We present in detail our case report, and then, a literature search in PubMed and Scopus was performed up to March 20, 2022, to review the reported cases of aortic thrombus associated with cocaine use. Results A 39-year-old man with a history of smoking and daily cocaine use was admitted to our stroke unit for acute left-hemispheric symptoms due to carotid-Sylvian occlusion. CT angiography of the supra-aortic trunks showed FLOAT involving the left common carotid artery. The thrombus was removed successfully by endovascular thrombectomy with recanalization of carotid-Sylvian occlusion. Our literature search yielded seven reported cases of aortic thrombus due to cocaine use revealed by lower limb ischemia (3 patients), renal infarction (1 patient), abdominal pain (1 patient), bowel ischemia (1 patient), and lower limb ischemia with renal infarction (1 patient). Conclusion Aortic thrombus should be suspected in patients without overt cardiovascular risk factors but with a recent history of cocaine use who presents with acute ischemic stroke.

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Section: Resultsmentioning

confidence: 99%

“…Floating aortic thrombi (FLOAT) are rare and mainly diagnosed after an embolic event such as acute lower limb ischemia, renal infarction, and bowel ischemia [ 1 – 3 ]. FLOAT are mainly secondary to atherosclerotic disease of the aortic wall [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

Floating aortic arch thrombus involving the left common carotid artery complicated with ischemic stroke associated with cocaine use

et al. 2022

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“…The types of surgery mainly include simple thrombus resection and aorta replacement. Simple resection is often used when a pedunculated thrombus attached at aortic wall with a narrow stalk [8] while a large sessile thrombus is apt to be dealt with the involved segment of aorta replacement to avoid recurrence [9]. Considering his previous thrombotic events, we thought he may have high risk of distal embolism during conservative treatment.…”

Section: Discussionmentioning

confidence: 98%

Large mural thrombus in the non-aneurysmal and non-atherosclerotic ascending aorta: a case report

Dai

Luo

et al. 2021

J Cardiothorac Surg

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Background The mural thrombus in the ascending aorta is rare, most of which are associated with aneurysm or atherosclerotic lesions, with high risks of causing catastrophic thrombotic events. A mural thrombus in the non-aneurysmal and non-atherosclerotic ascending aorta is exceptionally uncommon. Case presentation We reported a large mural thrombus in normal ascending aorta of an asymptomatic patient. Preoperative imaging confirmed the presence of the sessile thrombus located at the left anterior wall of ascending aorta. Given that it had the potential to cause fatal thrombotic complications, surgical removal and segment of ascending aorta replacement were executed. The patient had an uneventful recovery and discharged 14 days after surgery. Conclusions Anticoagulant is the therapeutic cornerstone of ascending aortic thrombus, but surgery should be performed aggressively when the thrombus is large or floating to avoid severe embolic complications or recurrence.

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Section: Discussionmentioning

confidence: 99%

Large Mural Thrombus in the Non-Aneurysmal and Non-atherosclerotic Ascending Aorta: A Case Report

Dai

Luo

et al. 2021

Preprint

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BackgroundThe mural thrombus in the ascending aorta is rare, most of which are associated with aneurysm or atherosclerotic lesions, with high risks of causing catastrophic thrombotic events. A mural thrombus in the non-aneurysmal and non-atherosclerotic ascending aorta is exceptionally uncommon.Case PresentationWe reported a large mural thrombus in normal ascending aorta of an asymptomatic patient. Preoperative imaging confirmed the presence of the sessile thrombus located at the left anterior wall of ascending aorta. Given that it had the potential to cause fatal thrombotic complications, surgical removal and segment of ascending aorta replacement were executed. The patient had an uneventful recovery and discharged 14 days after surgery.ConclusionsAnticoagulant is the therapeutic cornerstone of ascending aortic thrombus, but surgery should be performed aggressively when the thrombus is large or floating to avoid severe embolic complications or recurrence.

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Giant Aortic Thrombus in the Ascending Aorta and Perforation of Bowel Associated With Cocaine Use

Cited by 10 publications

References 6 publications

Floating aortic arch thrombus involving the left common carotid artery complicated with ischemic stroke associated with cocaine use

Floating aortic arch thrombus involving the left common carotid artery complicated with ischemic stroke associated with cocaine use

Large mural thrombus in the non-aneurysmal and non-atherosclerotic ascending aorta: a case report

Large Mural Thrombus in the Non-Aneurysmal and Non-atherosclerotic Ascending Aorta: A Case Report

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