Gingival Crevicular Fluid Prostaglandin E<sub>2</sub> and Thiobarbituric Acid Reactive Substance Levels in Smokers and Non‐Smokers With Chronic Periodontitis Following Phase I Periodontal Therapy and Adjunctive Use of Flurbiprofen

Kurtiş, Bülent; Tüter, Gülay; Serdar, Muhittin; Pınar, Selin; Demirel, İlkim; Toyman, Utku

doi:10.1902/jop.2007.060217

Cited by 24 publications

(18 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The present study has observed that smokers with chronic periodontitis showed lower GI and PBI and higher PI and CAL as compared to non-smokers with chronic periodontitis. In accordance with our study, various studies [22][23][24] have observed altered clinical parameters in smokers with chronic periodontitis compared to non-smokers.…”

Section: Discussionsupporting

confidence: 93%

Assessment of Some Biochemical Oxidative Stress Markers in Male Smokers with Chronic Periodontitis

et al. 2013

View full text Add to dashboard Cite

The present study aims to assess and compare the biochemical oxidative stress markers in male smokers and non-smokers with chronic periodontitis. One hundred thirty-four male chronic periodontitis patients and 64 apparently healthy male volunteers were recruited for the study. The periodontal status was evaluated by measuring gingival index, plaque index, papillary bleeding index and clinical attachment loss using UNC-15 probe. The biochemical markers estimated were total antioxidant capacity, RBC-superoxide dismutase, glutathione peroxidase, vitamin C, malondialdehyde and C-reactive protein.The obtained results indicate higher oxidative stress in chronic periodontitis. Smokers with chronic periodontitis show significantly higher periodontal clinical parameters and relatively higher systemic oxidative stress. Vitamin C estimation may be an important biochemical parameter in conjunction with clinical parameters for diagnosis of chronic periodontitis in smokers.

show abstract

Section: Discussionsupporting

confidence: 93%

Assessment of Some Biochemical Oxidative Stress Markers in Male Smokers with Chronic Periodontitis

et al. 2013

View full text Add to dashboard Cite

show abstract

“…The last product of the lipid peroxidation process, malondialdehyde (MDA), is a frequently used parameter in measuring the oxidative damage to the lipids resulting from free radicals [39]. Thiobarbituric acid reactive substances test (TBARS) is the most widely used test in the measurement of MDA levels [40, 41]. Some previous studies have shown that serum levels of MDA were increased in systemic diseases such as tuberculosis and that salivary levels of MDA were also significantly increased in periodontal diseases and reported that this increase in MDA levels is an important indicator of periodontal tissue destruction [38].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Oxidative Stress Biomarkers in Patients with Fixed Orthodontic Appliances

Özcan

Ceylan

Özcan³

et al. 2014

Disease Markers

View full text Add to dashboard Cite

Aim. The aim of this study was to examine the changes in the levels of interleukine-1 beta (IL-1β), tumor necrosis factor alpha (TNF-α), malondialdehyde (MDA), nitric oxide (NO), and 8-hydroxydeoxyguanosine (8-OHdG) in saliva and IL-1β, TNF-α, and NO in gingival crevicular fluid (GCF) samples of patients with fixed orthodontic appliances. Material and Method. The subject population consisted of 50 volunteers who were in need of orthodontic treatment with fixed orthodontic appliances. GCF and saliva samples were obtained from all individuals before treatment, at 1st month of treatment and at 6th month of treatment. Periodontal clinical parameters were measured. Samples were investigated to detect IL-1β, TNF-α, and 8-OHdG levels using ELISA method and NO and MDA levels using spectrophotometric method. Results. Since IL-1β level detected in GCF at the 6th month of orthodontic treatment is statistically significant according to baseline (P < 0.05), all other biochemical parameters detected both in saliva and in GCF did not show any significant change at any measurement periods. Conclusion. Orthodontic tooth movement and orthodontic materials used in orthodontic treatment do not lead to a change above the physiological limits that is suggestive of oxidative damage in both GCF and saliva.

show abstract

“…In a recent study, Tomasi and Wennström 35 reported additional benefits with the use of adjunctive local doxycycline in the treatment of smokers. Also, we should mention our previous investigation of the effects of SRP and the adjunctive use of flurbiprofen on the GCF PGE 2 and thiobarbituric acid reactive substance (TBARS) levels in smokers and non‐smokers with CP 36 . SRP plus flurbiprofen had more inhibitory effects on GCF levels of PGE 2 and TBARS in smokers compared to non‐smokers with CP.…”

mentioning

confidence: 92%

GCF MMP‐8 Levels in Smokers and Non‐Smokers With Chronic Periodontitis Following Scaling and Root Planing Accompanied by Systemic Use of Flurbiprofen

Kurtiş

Tüter

Serdar

et al. 2007

Journal of Periodontology

Self Cite

View full text Add to dashboard Cite

show abstract

Gingival Crevicular Fluid Prostaglandin E₂ and Thiobarbituric Acid Reactive Substance Levels in Smokers and Non‐Smokers With Chronic Periodontitis Following Phase I Periodontal Therapy and Adjunctive Use of Flurbiprofen

Abstract: These results suggest that additional flurbiprofen administration may have more inhibitory effects on GCF levels of PGE(2) and TBARS in the groups of smokers compared to non-smokers with CP.

Cited by 24 publications

References 46 publications

Assessment of Some Biochemical Oxidative Stress Markers in Male Smokers with Chronic Periodontitis

Assessment of Some Biochemical Oxidative Stress Markers in Male Smokers with Chronic Periodontitis

Evaluation of Oxidative Stress Biomarkers in Patients with Fixed Orthodontic Appliances

GCF MMP‐8 Levels in Smokers and Non‐Smokers With Chronic Periodontitis Following Scaling and Root Planing Accompanied by Systemic Use of Flurbiprofen

Contact Info

Product

Resources

About

Gingival Crevicular Fluid Prostaglandin E2 and Thiobarbituric Acid Reactive Substance Levels in Smokers and Non‐Smokers With Chronic Periodontitis Following Phase I Periodontal Therapy and Adjunctive Use of Flurbiprofen

Abstract: These results suggest that additional flurbiprofen administration may have more inhibitory effects on GCF levels of PGE(2) and TBARS in the groups of smokers compared to non-smokers with CP.

Cited by 24 publications

References 46 publications

Assessment of Some Biochemical Oxidative Stress Markers in Male Smokers with Chronic Periodontitis

Assessment of Some Biochemical Oxidative Stress Markers in Male Smokers with Chronic Periodontitis

Evaluation of Oxidative Stress Biomarkers in Patients with Fixed Orthodontic Appliances

GCF MMP‐8 Levels in Smokers and Non‐Smokers With Chronic Periodontitis Following Scaling and Root Planing Accompanied by Systemic Use of Flurbiprofen

Contact Info

Product

Resources

About

Gingival Crevicular Fluid Prostaglandin E₂ and Thiobarbituric Acid Reactive Substance Levels in Smokers and Non‐Smokers With Chronic Periodontitis Following Phase I Periodontal Therapy and Adjunctive Use of Flurbiprofen