Glass-Forming Tendency and Stability of Aqueous Solutions of Diethylformamide and Dimethylformamide

Baudot, Anne; Boutron, P.

doi:10.1006/cryo.1998.2112

Cited by 23 publications

(15 citation statements)

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“…Moreover, a deviation may exist at the highest cooling rate 320 K/min, due to the fact that the real cooling rate is smaller. However, it is clear that q max decreases as the compound concentration increases and it is apparent that the critical cooling rate decreases with increasing amino-alcohol concentration, as it is used to be for other cryoprotectants [1][2][3]29]. When comparing the glass-forming tendency of the two compounds, we can see from 40% to 45% (w/w) that 21AE is more effective than 31AP.…”

Section: Stability Of the Wholly Amorphous State On Warmingmentioning

confidence: 97%

“…The theoretical value of q, considered as before [1,2,4,5,11,29] to be proportional to x, is chosen such that its maximum value q max fits the experimental values. Since x ¼ 1 corresponds to q ¼ q max , x ¼ q=q max .…”

Section: Heats Of Solidification On Cooling and Glass-forming Tendencymentioning

confidence: 99%

“…4). The vitreous transition temperature T g is determined as usual [1] at the inflexion point between the limits at which the slope of the curve changes through the glass transition. The top of the devitrification peak is called T d as usual [1,2,5,11,29].…”

Section: Stability Of the Wholly Amorphous State On Warmingmentioning

confidence: 99%

“…The temperature T m of the end of ice melting can be defined, as for most of the solutions studied [1,2,5,11,29], as the top of the temperature of the ice melting peak on warming at the smallest warming rate (here 1 K/min). The corrections using the leading edge method [5,9,23] …”

Section: Stability Of the Wholly Amorphous State On Warmingmentioning

confidence: 99%

“…As usual [1,2,5,7], the stability of the amorphous state is defined by the critical warming rate v cwr above which there is not enough , and 45% (w/w) 21AE or 31AP. They are approximatively in agreement with theory [10] between 1 and 160 K/min.…”

Section: Stability Of the Wholly Amorphous State On Warmingmentioning

confidence: 99%

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Thermal study of simple amino-alcohol solutions

Baudot¹,

Cacela

Duarte

et al. 2002

Cryobiology

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Widely regarded as the most promising approach to long-term cryopreservation of organs for transplantation, vitrification is a process where liquid is transformed into a disordered solid state free from crystals, known as the amorphous state. The vitreous state is obtained by rapid cooling to cryogenic temperatures in the presence of antifreeze substances called cryoprotectants, such as polyalcohols, which are known to be very good vitrification agents. This work reports on the thermal properties of a new class of compounds, the amino-alcohols, studied for its similarity to the structure of the equivalent polyalcohols. We studied by differential scanning calorimetry the glass-forming tendency and stability of the amorphous state for de-ionized water solutions containing 2-amino-1-ethanol and 3-amino-1-propanol at the concentrations of 35%, 40%, 43%, and 45% (w/w). A comparison is made with previous results obtained by Mehl [Cryobiology 27 (1990) 687-688] on the same compounds under different experimental conditions. The results are also compared with those obtained by Boutron [Cryobiology 30 (1993) 87-97] for the corresponding dialcohols. A further comparison is made with a few results obtained for the 1-amino-2-propanol and the 2-amino-1-propanol tested under the same conditions. Ó 2002 Elsevier Science (USA). All rights reserved.

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Section: Stability Of the Wholly Amorphous State On Warmingmentioning

confidence: 97%