Glaukombehandlung mittels transskleraler Zyklophotokoagulation in Mikropulstechnik in einem „low‑income setting“

Kotula, Martin Andreas; Paust, K.; Wirdemann, Arno; Msigomba, Erick; Burusu, Liberator

doi:10.1007/s00347-022-01668-6

Cited by 2 publications

(2 citation statements)

References 14 publications

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“…In this study, we used a different device—diode laser FOX 810—with parameters recommended by the producer described in the method section. So far, there has only been one study published in a non-English journal where µCPC was performed on African patients with this device [ 8 ]. Authors obtained a success rate of 65% at 9 months follow-up with at least 20% IOP reduction in 20 patients with a mean energy of the device set at 127 J ± 10 J.…”

Section: Discussionmentioning

confidence: 99%

“…Until now, only one study has been published, in a non-English journal, where µCPC was performed on African patients with a diode laser FOX 810 (A.R.C. Laser, Nuremberg, Germany) with a success rate of around 65% at 9 months follow-up [ 8 ]. All other literature about micropulse cyclophotocoagulation published so far refers to the use of different devices.…”

Section: Introductionmentioning

confidence: 99%

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Microcyclophotocoagulation in Glaucoma Treatment: A Medium-Term Follow-Up Study

Bolek

Wylęgała

2023

JCM

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Background: This study aimed to assess the effectiveness and safety of transscleral microcyclophotocoagulation (µCPC) in patients with glaucoma for eighteen consecutive months. Methods: Sixty-one patients (64 eyes) with primary and secondary glaucoma were enrolled to undergo µCPC (diode laser FOX 810, A.R.C. Laser, Nuremberg, Germany). The primary outcome measures were intraocular pressure (IOP) reduction, success rates, glaucoma medication use, and visual acuity after µCPC. An IOP reduction of 20% compared to the baseline value without re-intervention was considered a successful treatment. Complete success was defined as cessation of antiglaucoma medications. Secondary outcome measures included intraoperative and postoperative complications. Measurements were performed preoperatively and at the first week, and 1, 3, 6, 12, and 18 months postoperatively. Results: The mean ± SD values of IOP preoperatively at 1 day, 1 week, 1, 3, 6, 12, and 18 months postoperatively were 25.1 ± 8.4 mmHg, 17.3 ± 4.5 mmHg (p < 0.001), 16.5 ± 6.1 mmHg (p < 0.001), 20.5 ± 8.3 mmHg (p < 0.001), 17.1 ± 6.2 mmHg (p < 0.001), 18.0 ± 7.1 mmHg (p < 0.001), 15.8 ± 3.2 mmHg (p < 0.001), and 17.0 ± 5.9 mmHg (p < 0.001), respectively. The mean IOP at the last follow-up was reduced by 32.5%. The decrease in the number of antiglaucoma medications was statistically significant at each follow-up visit compared to the baseline. The qualified success rate was 38.5%. Two patients at 18-month follow-up did not require the use of antiglaucoma medications—complete success rate—3.1%. During the follow-up period, twenty-five eyes (39.1%) that required retreatment due to nonachievement of the target IOP were considered as failures. Eleven patients (12 eyes—18.8%) were lost to follow-up. A total of 26 patients (27 eyes) were evaluated 18 months after µCPC. Hypotony was observed in one patient (1.6%) and uveitis in two patients (3.1%) after the procedure. There were no other significant intraoperative or postoperative complications observed. Conclusions: The µCPC is well tolerated and safe for reducing IOP in glaucoma patients in medium-term follow-up; however, success is moderate. Randomized, larger studies are needed to confirm the obtained results.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Microcyclophotocoagulation in Glaucoma Treatment: A Medium-Term Follow-Up Study

Bolek

Wylęgała

2023

JCM

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Efficacy and safety of high-intensity focused ultrasound cyclo-plasty in glaucoma

et al. 2022

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Background High-intensity focused ultrasound cyclo-plasty (UCP) is a recently developed glaucoma surgery. This study collected and analysed the clinical data of patients who underwent UCP to observe the efficacy and safety of this surgery in Chinese glaucoma patients. Methods This was a retrospective study. The clinical data of all the patients who underwent UCP at Affiliated Foshan Hospital, Southern Medical University, were collected and analysed to evaluate the efficacy and safety of UCP. The main outcome measure was intraocular pressure, and the secondary outcome measures were best corrected visual acuity (logMAR) and complications. Results Fifty-eight patients (61 eyes) were recruited for this study. IOP was dramatically decreased during the 12 months after UCP (p<0.05). The median IOP reduction during the 18 months post-procedure was more than 30%. The greatest reduction was at 1 month post-UCP (60.86%). The qualified success rate was more than 60% during the 18-month follow-up (Fig. 1). Poor follow up was found after 6-month post-UCP. The highest success rate was obtained at 7 days post-UCP (94.55%). No statistically significant decrease in BCVA in the vison group was observed at the follow-up visits, except for 1 day post-UCP. There was a statistically significant reduction in the use of IOP lowering medications during the 6 months post-UCP. No severe complications occurred. Conclusion UCP is a safe and effective procedure for primary and refractive glaucoma at least during the 6 months post-UCP procedure. Studies with longer follow-up time and better follow up are needed to further confirm the long-term efficacy and safety of UCP in Chinese glaucoma patients.

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Glaukombehandlung mittels transskleraler Zyklophotokoagulation in Mikropulstechnik in einem „low‑income setting“

Cited by 2 publications

References 14 publications

Microcyclophotocoagulation in Glaucoma Treatment: A Medium-Term Follow-Up Study

Microcyclophotocoagulation in Glaucoma Treatment: A Medium-Term Follow-Up Study

Efficacy and safety of high-intensity focused ultrasound cyclo-plasty in glaucoma

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