Global developments in HIV neurology

Wright, Edwina; Thakur, Kiran T.; Bearden, David; Birbeck, Gretchen L.

doi:10.1016/b978-0-444-63849-6.00019-0

Cited by 5 publications

(2 citation statements)

References 207 publications

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“…The HIV virus can infect several host cells; however, its main target is central nervous system (CNS) and Immune System cells (WRICHT et al, 2018;MELHUISH & LEWTWAITE, 2018). Studies indicate that in adults, the virus when in contact with the CNS can cause dementia, while in children the condition can be identified as encephalopathy, which in itself is an indicator of severe disease (MITCHELL, 2001;CHIRIBOGA et al, 2004;SIRIOS et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

Affordances and Development of Hiv-Exposed and Unexposed Infants

Corrêa¹,

Pádua²,

Sá³

2020

TeS

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Development of infants exposed to the HIV, due to contact with the virus and/or antiretroviral therapy during pregnancy and postnatal period, is a much discussed topic. The environment influences the infant´s overall development regardless of whether it has a risk factor, but even more so if any factor is present. AIM: to compare affordances in the environment and the development of infant exposed and not exposed to HIV. METHOD: cross-sectional study in which 40 exposed and 40 unexposed infants HIV of both sexes at the ages of 4, 8, 12 and 18 months of age were assessed using the Bayley III scale (motor, cognitive and language development)-and the AHEMD questionnaire addressed to parents about the environment and home stimulation. DATA ANALYSIS: Analysis of variance with two fixed factors and Tukey´s multiple comparisons method and Pearson´s linear correlation coefficient. RESULTS: No significant differences were found between the groups using the Bayley scale, but infants exposed to the virus presented higher values for the AHEMD scale fine motricity. Age differences were found for AHMED variables, regardless of group; and correlations for Bayley with the AHEMD scale total score. CONCLUSION: HIVexposed infants do not show a delay in motor, cognitive and language development compared to unexposed infants. On the contrary, they may present equal or even better

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Section: Introductionmentioning

confidence: 99%

Affordances and Development of Hiv-Exposed and Unexposed Infants

Corrêa¹,

Pádua²,

Sá³

2020

TeS

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“…2 Moreover, many individuals with neurologic infections are living longer, and there is increased interest in the long-term sequelae of chronic neuroinfectious disease in the United States and worldwide. 3,4 Along with the shifting epidemiology and increased appreciation of the consequences of neurologic infections, there have been changes in training paradigms. 5 While neuropathology comprised the major pillar of training in neuroinfectious diseases several decades ago, newer diagnostic and treatment modalities, recognition of autoimmune syndromes that necessitate distinction from neurologic infections, opportunities to interface with other specialists in the care of patients, and a changing regulatory environment with respect to medical training have resulted in additional educational needs.…”

mentioning

confidence: 99%

Building a neuroinfectious disease consensus curriculum

et al. 2019

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ObjectiveTo delineate a comprehensive curriculum for fellowship training in neuroinfectious diseases, we conducted a modified Delphi approach to reach consensus among 11 experts in the field.MethodsThe authors invited a diverse range of experts from the American Academy of Neurology Neuro-Infectious Diseases (AAN Neuro-ID) Section to participate in a consensus process using a modified Delphi technique.ResultsA comprehensive list of topics was generated with 101 initial items. Through 3 rounds of voting and discussion, a curriculum with 83 items reached consensus.ConclusionsThe modified Delphi technique provides an efficient and rigorous means to reach consensus on topics requiring expert opinion. The AAN Neuro-ID section provided the pool of diverse experts, the infrastructure, and the community through which to accomplish the consensus project successfully. This process could be applied to other subspecialties and sections at the AAN.

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