Global initiative for congenital toxoplasmosis: an observational and international comparative clinical analysis

Abstract

Globally, congenital toxoplasmosis remains a significant cause of morbidity and mortality, and outbreaks of infection with T. gondii represent a significant, emerging public health burden, especially in the developing world. This parasite is a threat to public health. Disease often is not recognized and is inadequately managed. Herein, we analyze the status of congenital toxoplasmosis in Morocco, Colombia, the United States, and France. We identify the unique challenges faced by each nation in the implementation of optimal approaches to congenital toxoplasmosis as a public health problem. We suggest that developed and developing countries use a multipronged approach, modeling their public health management protocols after those in France. We conclude that education, screening, appropriate treatment, and the development of novel modalities will be required to intervene successfully in caring for individuals with this infection. Gestational screening has been demonstrated to be cost-effective, morbidity-sparing, and life-saving. Recognition of the value and promise of public health interventions to prevent human suffering from this emerging infection will facilitate better patient and societal outcomes.

Toxoplasma gondii infection and toxoplasmosis in North Africa: a review

“…This is may be due to the recognition that toxoplasmosis is a significant public health challenge and to public awareness. In Morocco for example, awareness about the risk of this zoonosis is increasing thanks to new initiatives and research established by the Ministry of Health [46].…”

“…Morocco's health policy, like in Tunisia and Algeria, is influenced by French approaches that represent a strong benchmark for countries planning to set up a national program against toxoplasmosis [46]. In fact, France reported a decrease in the prevalence and severity of toxoplasmosis after the implementation of mandatory gestational screening, with standardized screening and treatment protocols in addition to public awareness.…”

“…In general, there was a lack of diversity in techniques and only serological methods were used to detect human and animal infection. This could be explained by the lack of molecular diagnostic tools especially in state laboratories, and the limited information regarding contributing risk factors [46].…”

Ações de educação em saúde sobre parasitoses humanas em escolas públicas no município de Jataí, Goiás

“…A toxoplasmose pode se manifestar através da corioretinite em adultos ou ser consequência de uma infecção congênita pelo parasito. Sendo a última, importante causa de abortos e má formação fetal (BISSATI et al, 2018).…”

Association between Toxoplasma gondii infection and thyroid dysfunction: a case-control seroprevalence study

“…Toxoplasma gondii (T. gondii) is an obligated intracellular protozoan parasite [1]. T. gondii is responsible of morbidity and mortality worldwide [2][3][4]. This parasite causes a disease so called toxoplasmosis which often is not recognized and is inadequately managed [3].…”