Glucose oxidase immobilized PANI cladding modified fiber optic intrinsic biosensor for detection of glucose

Pahurkar, V. G.; Tamgadge, Y. S.; Gambhire, A.B.; Muley, G.G.

doi:10.1016/j.snb.2014.12.125

Cited by 42 publications

(14 citation statements)

References 47 publications

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“…It occurs when the pancreas does not produce enough insulin or the body cannot effectively use the insulin it produces (Zhong et al, 2015). Most of the meters are based on the glucose oxidase modified electrodes (Pahurkar et al, 2015). Blood glucose monitoring is an integral part of diabetes management, and in this regard self-monitoring of glucose has been considered by many as one of the most important advances in management of the disease ever since the discovery of insulin (St John et al, 2010).…”

Section: Glucose Oxidase-based Glucose Biosensors For Diabetesmentioning

confidence: 99%

Enzymatic Biosensors

Karunakaran¹,

Thangamuthu²,

Sethy

2015

Biosensors and Bioelectronics

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Section: Glucose Oxidase-based Glucose Biosensors For Diabetesmentioning

confidence: 99%

Enzymatic Biosensors

Karunakaran¹,

Thangamuthu²,

Sethy

2015

Biosensors and Bioelectronics

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“…Optical method also enabled to sense in deeper lying or less accessible region of the body [3,39]. Muley et al [40] has modified optical fibre by coating polyaniline as support matrix due to its proton coupled redox chemistry and its resulting pH dependent properties. The modified optical fibre was used for glucose sensing as enzyme electrodes after immobilization GOx [41].…”

Section: Introductionmentioning

confidence: 99%

Optical fibre based non-enzymatic glucose sensing over Cu2+-doped polyaniline hybrid matrix

Shukla

Demir

Govender

et al. 2017

Sensors and Actuators B: Chemical

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The opto-chemical glucose sensing over cupric ion doped polyaniline (Cu +2 /PANI) hybrid polymer matrix coated glass rod based optode has been demonstrated.Cu +2 /PANI hybrid matrix was synthesized by in situ chemical polymerization of intrinsically functionalized aniline. Furthermore, developed optode has been explored for direct oxidisation of glucose on Cu +2 /PANI hybrid matrix for non-enzymatic glucose sensing employing O-dianisidine indicator system. The proposed glucose sensor works well in range of 50 mg/dL-200 mg/dL with response time of 15 s in artificial as well as in biological samples along with 40 days of lifespan.

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“…Current FDA-approved blood glucose devices are based on biocatalytic elements such as glucose oxidase [1][2][3][4][5], glucose dehydrogenase [6] and hexokinase [7]. An alternative technology for glucose sensing employs bioaffinity elements such as the glucose binding protein (GBP) [8][9][10][11][12][13].…”

Section: Introductionmentioning

confidence: 99%

Fluorophore-labeled bioengineered glucose binding protein for measurement of transdermal glucose

Tiangco¹,

Brown²,

Sevilla³

et al. 2016

actamanil

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Measurement of glucose is an important component of care in the intensive care unit. Current methodologies for glucose monitoring include enzymatic-based laboratory analyzers, point of care testing and continuous glucose monitoring systems that all require breaking the skin. This study focuses on the development of a glucose biosensor to measure transdermal glucose (TG) by noninvasive passive diffusion. The H152C glucose binding protein (GBP) labeled with the polarity-sensitive dye BADAN (6-bromoacetyl-2dimethylaminonaphthalene) was prepared and characterized with the aim of producing a biosensor with an operating range at micromolar levels compatible with TG concentrations. The BADAN-labeled GBP exhibited a large fluorescence intensity increase (228%) upon addition of a saturating concentration of glucose. The glucose binding constant was calculated to be (K d ) 1.124 ± 0.2361 M. The biosensor has a linear operating range of 0.030-0.460 M, making it suitable for monitoring transdermal glucose. The use of the biosensor was demonstrated by measuring TG collected by passive diffusion of glucose through the skin of healthy adult subjects. Results showed that the H152C GBP labeled with BADAN is capable of measuring TG and can be used for noninvasive glucose sensing.

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Glucose oxidase immobilized PANI cladding modified fiber optic intrinsic biosensor for detection of glucose

Cited by 42 publications

References 47 publications

Enzymatic Biosensors

Enzymatic Biosensors

Optical fibre based non-enzymatic glucose sensing over Cu2+-doped polyaniline hybrid matrix

Fluorophore-labeled bioengineered glucose binding protein for measurement of transdermal glucose

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