“…Figure 3 also shows some unassigned peaks at 55.05° and 57.66° indicated with (*) which may come from compounds present in the remaining extract that are complexed with AgMt NPs. Precisely these molecules adsorbed on nanoparticles surface provide stability to the system and confer additional therapeutic properties related to these compounds nature 44 – 46 . Figure 3 X-Ray Diffraction (XRD) pattern of AgMt Nps powder.…”
In this work we use Mimosa tenuiflora (MtE) extracts as reducing agents to synthesize silver nanoparticles (AgMt NPs) which were characterized by DPPH and Total Polyphenols Assays, UV–visible, X-ray diffractometer (XRD), high-resolution transmission electron microscopy (HRTEM), X-ray photoelectron spectroscopy (XPS) and Thermogravimetric analysis (TGA). AgMt NPs possess average sizes of 21 nm and fcc crystalline structure, it was also confirmed that the MtE is present in the AgMt NPs even after the cleaning protocol applied. Subsequently, carbopol hydrogels were made and the MtE and the synthesized AgMt NPs were dispersed in different gels (MtE-G and AgMt NPs-G, respectively) at 100 µg/g concentration. The gels were characterized by UV–Vis, IR, and rheology. Antimicrobial tests were performed using Staphylococcus aureus and Escherichia coli. Burn wound healing was evaluated in a second-degree burn injury on a Wistar rats model for 14 days and additional skin biopsies were examined with histopathological analysis. Gel with commercial silver nanoparticles (Ag NPs) was prepared and employed as a control on the biological assays. Hydrogel system containing silver nanoparticles synthesized with Mimosa tenuiflora (AgMt NPs-G) is a promising therapeutic strategy for burn wound healing, this due to bactericidal and anti-inflammatory effects, which promotes a more effective recovery (in percentage terms) by damaged area.
“…Figure 3 also shows some unassigned peaks at 55.05° and 57.66° indicated with (*) which may come from compounds present in the remaining extract that are complexed with AgMt NPs. Precisely these molecules adsorbed on nanoparticles surface provide stability to the system and confer additional therapeutic properties related to these compounds nature 44 – 46 . Figure 3 X-Ray Diffraction (XRD) pattern of AgMt Nps powder.…”
In this work we use Mimosa tenuiflora (MtE) extracts as reducing agents to synthesize silver nanoparticles (AgMt NPs) which were characterized by DPPH and Total Polyphenols Assays, UV–visible, X-ray diffractometer (XRD), high-resolution transmission electron microscopy (HRTEM), X-ray photoelectron spectroscopy (XPS) and Thermogravimetric analysis (TGA). AgMt NPs possess average sizes of 21 nm and fcc crystalline structure, it was also confirmed that the MtE is present in the AgMt NPs even after the cleaning protocol applied. Subsequently, carbopol hydrogels were made and the MtE and the synthesized AgMt NPs were dispersed in different gels (MtE-G and AgMt NPs-G, respectively) at 100 µg/g concentration. The gels were characterized by UV–Vis, IR, and rheology. Antimicrobial tests were performed using Staphylococcus aureus and Escherichia coli. Burn wound healing was evaluated in a second-degree burn injury on a Wistar rats model for 14 days and additional skin biopsies were examined with histopathological analysis. Gel with commercial silver nanoparticles (Ag NPs) was prepared and employed as a control on the biological assays. Hydrogel system containing silver nanoparticles synthesized with Mimosa tenuiflora (AgMt NPs-G) is a promising therapeutic strategy for burn wound healing, this due to bactericidal and anti-inflammatory effects, which promotes a more effective recovery (in percentage terms) by damaged area.
“…The size of silver nanoparticles synthesized using the antioxidant constituents from blackberry, blueberry, pomegranate, and turmeric extracts was found to between 20 and 500 nm size, depending on the nature of extracts and method of preparation [121]. P. maderaspatensis proved to be a good catalyst for the initiation of the reaction, which rapidly produced AgNPs within a short span of 24 h with a particle size as 59 nm [122]. The zeta potential value (−18 mV) of AgNPs synthesized by Delonix elata after 24 h incubation indicates its stability [123].…”
Section: Conventional Methods Of Nanoparticle Synthesis: a Critical Viewmentioning
Silver nanoparticles possess unique properties which find myriad applications such as antimicrobial, anticancer, larvicidal, catalytic, and wound healing activities. Biogenic syntheses of silver nanoparticles using plants and their pharmacological and other potential applications are gaining momentum owing to its assured rewards. This critical review is aimed at providing an insight into the phytomediated synthesis of silver nanoparticles, its significant applications in various fields, and characterization techniques involved.
“…Traditionally, gold and other molecules [75][76][77][78] have been used in nanoparticle-predicted drug delivery applications, but the use of silver has been restricted due to the complexity in synthesis; when functionalized using the classic salt aging procedure, there was a reduction in durability, and there were worries regarding silver toxicity in the past. Clinical application of silver nanoparticles as beneficial antibacterial treatments in wound care and also current in vivo studies showing that systemic exposure to silver nanoparticles is safe to have sparked interest in biomedical research involving silver nanoparticles.…”
Section: Review On Silver Nanoparticles As Drug Delivery Vehiclesmentioning
Silver nanoparticles in the range from 1 to 100 nm are widely used in industrial applications as catalysis, electronics, and photonics, and they have unique properties such as optical, electrical, and magnetic characteristics that can be used as antimicrobial, biosensor textile, cosmetics, composite fibers, and electronic components and to amend shelf life of food substances. The main objective of the present review was to focus on formulation methods of silver nanoparticles with recent advances and future aspects. Silver nanoparticle shows very high potential towards biological applications. Several physicals, chemical, and various biological techniques have been employed to synthesize and stabilize silver nanoparticles. For the manufacture of silver nanoparticles, multiple methods, including chemical simplification with different natural and inorganic decreasing agents, physicochemical reduction, electrochemical procedures, and radiolysis, are employed. Silver nanoparticles are the single most manufacturer-identified material that can be used in all nanotechnology products. They can be used in food packing polymers to enhance the shelf lifespan. The present review is aimed at different types of synthesis and details of silver nanoparticles used as drug delivery vehicles, antibacterial activity, toxicity, recent advances, and future aspects.
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