Guidelines for measurement skin colour and erythema A report from the Standardization Group of the European Society of Contact Dermatitis*

Fullerton, Ann; Fischer, Tobias W.; Lahti, Arto; Wilhelm, Klaus‐Peter; Takiwaki, Hirotsugu; Serup, Jørgen

doi:10.1111/j.1600-0536.1996.tb02258.x

Cited by 356 publications

(262 citation statements)

References 23 publications

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“…It is also important for the operator to hold the chromameter head in such a way that variation in pressure is avoided (Schwarb et al, 1999). The presence of hair and variations in skin glossiness related to the amount of water and lipid on the skin surface, scarring, uneven skin tone, etc., can influence the data obtained (Fullerton et al, 1996). As a result, it is important to avoid these areas of the skin to achieve reliable and reproducible data.…”

Section: Methodsmentioning

confidence: 99%

Strategies for the Bioequivalence Assessment of Topical Dermatological Dosage Forms

Kanfer¹

2010

JBB

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Section: Methodsmentioning

confidence: 99%

Strategies for the Bioequivalence Assessment of Topical Dermatological Dosage Forms

Kanfer¹

2010

JBB

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“…Before the measurements, all volunteers had to rest in a room, under constant environmental conditions of 22 ± 2°C and 55 ± 5% relative humidity, for at least 20 min 12,14 . The evaluation began at the same time (at some time between 8:00 and 12:00) for all visits.…”

Section: Assessmentsmentioning

confidence: 99%

“…TEWL and pH were only measured at the centre so as to minimize the skin stress resulting from these types of measurement. The colour and redness, moisture content, pH, and TEWL were measured (noninvasively) using, respectively, a Mexameter MX 18, a Corneometer CM 825, a Skin-pH-Meter PH 900, and a Tewameter TM 300 (all from Courage + Khazaka Electronic GmbH) 12,14,15 . Clinical signs and symptoms of skin irritation were used to evaluate the mildness of product.…”

Section: Assessmentsmentioning

confidence: 99%

“…In addition, all skin signs and symptoms which occurred during the study period were recorded in a diary twice a day by the volunteers themselves. If symptoms www.scienceasia.org appeared, clinical evaluation of skin irritation by a dermatologist was registered using the visual scoring scales of Frosch & Kligman and COLIPA 12,13,16 based on the three main types of skin lesions (erythema, scaling, and oedema domains).…”

Section: Assessmentsmentioning

confidence: 99%

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Maenthaisong¹,

Chaiyakunapruk²,

Warnnissorn³

et al. 2009

ScienceAsia

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Cleansing lotion containing 8% w/w tamarind pulp extract was prepared and tested for its clinical effects on skin properties. The study was performed using 38 healthy Thai female volunteers, and consisted of a home-use, doubleblind, randomized side of face and placebo controlled trial. The test product (emulsion with the extract) and the placebo product (emulsion without the extract) were applied and gently massaged on each side of facial skin for 2 minutes twice daily for 8 weeks and the difference in skin colour between test and placebo side of face was measured. In addition, redness, moisture content, pH and transepidermal water loss (TEWL) of skin, adverse events, subject's satisfaction, and compliance of volunteers were assessed. We found that the melanin value on the side where the test product was applied was significantly less than that of the other side at week 4 (p < 0.015). The mean differences between the test and the placebo side of all skin parameters including melanin value, pH and moisture content elasticity were not significant (p > 0.05) at the end of study (week 8). Erythema and TEWL of the skin were not different between the side on which the test was applied and the placebo side indicating that the product was safe. In addition, most volunteers were satisfied with the cleansing effect of the product containing the extract.

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“…Therefore, green and red channel images of FCI were used to extract out information on the biopterins, which have 350 nm excitation and 450 nm emission wavelengths while at the same time minimizing the porphyrins contribution, which has 400-450 nm excitation and 630 and 690 nm emission wavelengths. 29,30 In order to objectively evaluate the degree of vitiligo, a vitiligo index (VI) image was computed as follows: (7) where G and R represent the normalized green and red channel images of the FCI, respectively. The VI image minimizes the overlapped spectral response between green and red channel images containing the biopterin and porphyrin signals, respectively.…”

Section: Fcismentioning

confidence: 99%

Multimodal facial color imaging modality for objective analysis of skin lesions

2008

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We introduce a multimodal facial color imaging modality that provides a conventional color image, parallel and cross-polarization color images, and a fluorescent color image. We characterize the imaging modality and describe the image analysis methods for objective evaluation of skin lesions. The parallel and cross-polarization color images are useful for the analysis of skin texture, pigmentation, and vascularity. The polarization image, which is derived from parallel and crosspolarization color images, provides morphological information of superficial skin lesions. The fluorescent color image is useful for the evaluation of skin chromophores excited by UV-A radiation. In order to demonstrate the validity of the new imaging modality in dermatology, sample images were obtained from subjects with various skin disorders and image analysis methods were applied for objective evaluation of those lesions. In conclusion, we are confident that the imaging modality and analysis methods should be useful tools to simultaneously evaluate various skin lesions in dermatology.

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Guidelines for measurement skin colour and erythema A report from the Standardization Group of the European Society of Contact Dermatitis*

Cited by 356 publications

References 23 publications

Strategies for the Bioequivalence Assessment of Topical Dermatological Dosage Forms

Strategies for the Bioequivalence Assessment of Topical Dermatological Dosage Forms

Untitled

Multimodal facial color imaging modality for objective analysis of skin lesions

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