Guidelines for paediatric bone scanning with 99mTc-labelled radiopharmaceuticals and 18F-fluoride

Stauß, Jan; Hahn, Klaus; Mann, M. D.; Palma, Diego De

doi:10.1007/s00259-010-1492-3

Cited by 46 publications

(16 citation statements)

References 42 publications

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“…The guidelines for clinical indications, image acquisition, image processing, and image interpretation of bone scans in children with either 99m Tc-labeled radiotracers and 18 F-NaF PET have been published (19). Pediatric activity is typically weight-based at 2.22 MBq/kg (0.06 mCi/kg), with a range of 18.5–185 MBq (0.5–5 mCi).…”

Section: Pediatricsmentioning

confidence: 99%

Sodium 18F-Fluoride PET/CT of Bone, Joint, and Other Disorders

Jadvar

Desai

Conti

2015

Seminars in Nuclear Medicine

113

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The use of 18F-sodium fluoride (18F-NaF) with positron emission tomography-computed tomography (PET/CT) is increasing. This resurgence of an old tracer has been fueled by several factors including superior diagnostic performance over standard 99mTc-based bone scintigraphy, growth in the availability of PET/CT imaging systems, increase in the number of regional commercial distribution centers for PET radiotracers, the recent concerns about potential chronic shortages with 99mTc based radiotracers, and the recent decision by the Centers for Medicare and Medicaid Services to reimburse for 18F-NaF PET/CT for evaluation of patients with known or suspected bone metastases through the National Oncologic PET Registry. The major goal of this article is to review the current evidence on the diagnostic utility of 18F-NaF in the imaging assessment of bone and joint in a variety of clinical conditions.

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Section: Pediatricsmentioning

confidence: 99%

Sodium 18F-Fluoride PET/CT of Bone, Joint, and Other Disorders

Jadvar

Desai

Conti

2015

Seminars in Nuclear Medicine

113

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“…Bone scintigraphy was performed on 712 TMJs in 356 symptomatic patients. An intravenous dose of 99m Tc‐hydroxymethylene diphosphonate, determined by 740 MBq × body weight/70 kg, was injected intravenously (Stauss, Hahn, Mann, & De Palma, ). After 3 hr, images were acquired using dual‐head gamma‐cameras (ECAM, Siemens, Munich, Germany) equipped with a low‐energy, high‐resolution collimator.…”

Section: Methodsmentioning

confidence: 99%

Prediction of painful temporomandibular joint osteoarthritis in juvenile patients using bone scintigraphy

Lee

Hong

Chun

2019

Clinical & Exp Dental Res

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The study aims to evaluate whether bone scintigraphy is effective in diagnosing temporomandibular joint (TMJ) osteoarthritis (OA) in juvenile patients. A retrospective study was conducted with 356 consecutive patients with TMJ–OA who were clinically assessed according to the Research Diagnostic Criteria for Temporomandibular Disorders. Patients were assigned to three groups based on their ages: Group 1: aged 12–16 years; Group 2: aged 17–19 years; and Group 3: aged 20 years. Additionally, we performed qualitative and quantitative analyses of bone scintigraphy images for the TMJ uptake ratio of the involved joint. The diagnostic rate of TMJ–OA (n = 356, 100%), and the overall presence of subjective pain (n = 282, 77.3%) was closest to the results of bone scintigraphy (n = 333, 91.2%). In addition, reported TMJ pain was significantly associated only with the results of bone scintigraphy and not with the results of panoramic radiography or cone beam computed tomography (CBCT) in all age groups. With CBCT as the reference standard, the optimal cutoff values of the uptake ratio for the diagnosis of TMJ–OA were 2.171 and 2.017 in Groups 1 and 2, respectively (P value < 0.05). Our results suggest that bone scintigraphy can be considered a useful modality for diagnosing TMJ–OA in juvenile patients.

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“…The injected dose was adapted to the size of the child, according to the European Association of Nuclear Medicine guidelines. 3 SPECT studies with iterative reconstruction were sometimes added to the planar images.…”

Section: Methodsmentioning

confidence: 99%