Healing of intra‐bony defects following treatment with a composite bovine‐derived xenograft (Bio‐Oss Collagen) in combination with a collagen membrane (Bio‐Gide PERIO)

Sculean, Anton; Chiantella, Giovanni Carlo; Windisch, Péter; Arweiler, Nicole Birgit; Brecx, M; Gera, István

doi:10.1111/j.1600-051x.2005.00758.x

Cited by 72 publications

(64 citation statements)

References 21 publications

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“…These grafting materials are also referred to as natural bone minerals, since proprietary processes are suggested to remove all cells and proteinaceous material, leaving behind an inert bone scaffold exhibiting a specific three-dimensional surface structure 42 . Recently, a natural bone mineral was coated with porcine derived collagen to render its surface even more attractive for cell adhesion (GBO, BioOss Collagen 1 ) 35,40 . Amongst the alloplastic materials, HA and tricalcium phosphate (TCP) were most commonly used for bone regeneration in combination with GBR and well accepted due to lack of possible disease transmission 5,16 .…”

mentioning

confidence: 99%

Immunohistochemical characterization of wound healing at two different bone graft substitutes

Sager

Ferrari

Wieland³

et al. 2012

International Journal of Oral and Maxillofacial Surgery

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mentioning

confidence: 99%

Immunohistochemical characterization of wound healing at two different bone graft substitutes

Sager

Ferrari

Wieland³

et al. 2012

International Journal of Oral and Maxillofacial Surgery

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“…Moreover, the osseointegration period was confirmed to range between 9 and 18 months. On the other hand, bovine bone matrix showed, in the same conditions, a longer resorption time, even with controversial histomorphometrical outcomes (28). At the end of this study, the reported outcomes showed a strong bone regeneration, with a bone regeneration mean value of 7.85±1.9 mm.…”

Section: Discussionmentioning

confidence: 49%

Pediatric patients tolerance: a comparative study about using of Er:YAG laser and self-adhesive flowable composite for treatment of primary decayed teeth

Vozza¹

2016

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SummaryAim. Hydroxyapatite (PA) has a chemical composition and physical structure very similar to natural bone and therefore it has been considered to be the ideal biomaterial able to ensure a biomimetic scaffold to use in bone tissue engineering. The aim of this study is to clinically test hydroxyapatite used as osteoconductive biomaterial in the treatment of periodontal bone defects. Clinical and radiological evaluations were conducted at 6, 12 and 18 months after the surgery. Materials and methods. Forty patients with 2-and 3-wall intrabony pockets were enrolled in this study. PPD, CAL, radiographic depth (RD) and angular defects were preoperatively measured. After surgery, patients were re-evaluated every 6 months for 18 months. Statistical analyses were also performed to investigate any differences between preoperative and postoperative measurements. Results. Paired t-test samples conducted on the data obtained at baseline and 18 months after, showed significant (p<0.01) differences in each measurement performed. The role of preoperative RD was demonstrated to be a significant key factor (p<0.01). A relevant correlation between preoperative PPD and CAL gain was also found. Conclusions.Within the limitations of this study, the absence of anatomical variables, except the morphology of the bone defect, emphasizes the importance of the proper surgical approach and the graft material used.

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“…Collagen maintains inorganic particles and blood clots, and has excellent formability, which allows it to be shaped to fit defects. These properties and other make collagen the most useful material for preparing composite materials [18,48]; furthermore, its safety has been well proven in clinical practice. However, no material has ideal properties for bone grafts, and, thus, efforts to identify better new materials are ongoing.…”

Section: Discussionmentioning

confidence: 99%

The Effect of Bisphasic Calcium Phosphate Block Bone Graft Materials with Polysaccharides on Bone Regeneration

et al. 2017

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In this study, bisphasic calcium phosphate (BCP) and two types of polysaccharide, carboxymethyl cellulose (CMC) and hyaluronic acid (HyA), were used to fabricate composite block bone grafts, and their physical and biological features and performances were compared and evaluated in vitro and in vivo. Specimens of the following were prepared as 6 mm diameter, 2 mm thick discs; BPC mixed with CMC (the BCP/CMC group), BCP mixed with crosslinked CMC (the BCP/c-CMC group) and BCP mixed with HyA (the BCP/HyA group) and a control group (specimens were prepared using particle type BCP). A scanning electron microscope study, a compressive strength analysis, and a cytotoxicity assessment were conducted. Graft materials were implanted in each of four circular defects of 6 mm diameter in calvarial bone in seven rabbits. Animals were sacrificed after four weeks for micro-CT and histomorphometric analyses, and the findings obtained were used to calculate new bone volumes (mm3) and area percentages (%). It was found that these two values were significantly higher in the BCP/c-CMC group than in the other three groups (p < 0.05). Within the limitations of this study, BCP composite block bone graft material incorporating crosslinked CMC has potential utility when bone augmentation is needed.

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Healing of intra‐bony defects following treatment with a composite bovine‐derived xenograft (Bio‐Oss Collagen) in combination with a collagen membrane (Bio‐Gide PERIO)

Abstract: Within the limits of the present study, it can be concluded that the combination of BDX Coll+GTR resulted in significantly higher CAL gains than treatment with access flap surgery alone, and thus appears to be a suitable alternative for treating intra-bony periodontal defects.

Cited by 72 publications

References 21 publications

Immunohistochemical characterization of wound healing at two different bone graft substitutes

Immunohistochemical characterization of wound healing at two different bone graft substitutes

Pediatric patients tolerance: a comparative study about using of Er:YAG laser and self-adhesive flowable composite for treatment of primary decayed teeth

The Effect of Bisphasic Calcium Phosphate Block Bone Graft Materials with Polysaccharides on Bone Regeneration

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