Health-related quality of life in patients with chronic hepatitis C during combined antiviral therapy

Abstract

Assessment of health-related quality of life in patients with chronic hepatitis C, as a technique for determining the tolerability of complex antiviral therapy.Methods: а comprehensive examination of 106 patients with a diagnosis of chronic hepatitis C was performed before and after the end of the combination antiviral therapy.Results of the study: after therapy on all scales of the physical component of health, higher rates were observed in men. Significantly differences (p < 0.05) were obtained in the following areas: physical functioning (PF), role-based functioning due to physical condition (RP) and general health status (GH). According to the scales of the mental component of health, the indicators of quality of life in men also exceed the obtained values in women, however, significant differences (p < 0.05) are established only on the scale of role-based functioning due to the emotional state (RE).