Health-related quality of life in Italian patients with systemic lupus erythematosus. I. Relationship between physical and mental dimension and impact of age

Rinaldi, S.

doi:10.1093/rheumatology/keh397

Cited by 82 publications

(67 citation statements)

References 14 publications

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“…Similarly, Rinaldi et al, 19 when examining the QOL of Italian women in a cohort of 126 patients with the disease and 96 healthy controls, found that mental and physical components were reduced only in patients with active disease.…”

Section: Discussionmentioning

confidence: 82%

“…17 Other studies show similarity to the results of this research with respect to mean age at the time of diagnosis. 2,16,[18][19][20]24 The diagnosis of SLE is always a nuisance, 21 leaving young women anxious because it occurs in a productive and crucial phase of their life, a time to stabilize their relationships, constitute a family, or choose a career. The author's argument quoted previously is consistent with the results of this study, as the SLE patients were on average 34 years old, but at the time of SLE diagnosis they were on average six years younger.…”

Section: Discussionmentioning

confidence: 99%

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Qualidade de vida relacionada à saúde em pacientes com lúpus eritematoso sistêmico no Centro-Oeste do Brasil

Reis¹,

Costa²

2010

Rev. Bras. Reumatol.

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Introduction/Objective: Evaluate the quality of life (QOL) of women with systemic lupus erythematosus (SLE) and the association between QOL domains, measured by the World Health Organization Quality of Life Group (WHOQOL-100) assessment instrument, and disease activity. Patients and Methods: A cross-sectional analytic study involving 95 patients with SLE, according to the American College of Rheumatology (ACR) criteria, aged 20-49 years, attended at the University Center of Universidade Federal de Mato Grosso do Sul, Campo Grande, MS. We used the following instruments: demographic and clinical data collection form and WHOQOL-100 instrument. Evaluation of disease activity was performed by SLEDAI. On statistical analysis, we applied Student's t-test, ANOVA, and Pearson's correlation. Results: Group-case: 79 female with mild to moderate SLE activity (SLEDAI = 1-10) and severe activity (SLEDAI ≥ 11). Control group: 16 female with inactive SLE (SLEDAI = 0). All domains of WHOQOL-100 proved to be affected, with significant difference (P < 0.005) between the case and control groups in which there was a better perception of QOL in the domain Spirituality and worst perception of QOL in the domain Environment. When confronting QOL domains with education, we detected a significant difference (P < 0.05) in the Physical, Psychological, Level of independence, and Environment domains. The comparison between QOL and disease activity was significant (P < 0.005) in three domains: Physical, Psychological, and Environment. Conclusion: SLE with intense activity determines a worse QOL condition than inactive SLE. The assessment of QOL enables the knowledge of disease and treatment impact in a contextualized way, which can render more appropriate and more comprehensive interventions.

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Section: Discussionmentioning

confidence: 82%

Section: Discussionmentioning

confidence: 99%

Qualidade de vida relacionada à saúde em pacientes com lúpus eritematoso sistêmico no Centro-Oeste do Brasil

Reis¹,

Costa²

2010

Rev. Bras. Reumatol.

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“…Mientras por el contrario, otros estudios han hallado una CVRS más desfavorable en pacientes con LES en comparación con muestras de control sanas y aún más con otras enfermedades crónicas (Abu-Shakra, et. al., 1999;Alarcón, et al, 2004;Jolly, 2005;Kulczycka, et al, 2008;Lash, 1998;Meenakshi, 2005;Rinaldi, et al, 2001;Rinaldi, et al, 2004).…”

Section: Discussionunclassified

Calidad de vida relacionada con la salud, factores psicológicos y fisiopatológicos en pacientes con diagnóstico de Lupus Eritematoso Sistémico - LES

et al. 2010

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ResumenEl objetivo de este estudio fue analizar, por un lado, los niveles de ansiedad, depresión, apoyo social, índice de actividad lúpica, fibromialgia, daño orgánico y renal, tiempo de diagnóstico de la enfermedad y factores sociodemográficos en 78 pacientes con diagnóstico de Lupus Eritematoso Sistémico; y analizar el efecto de estas variables sobre la calidad de vida relacionada con la salud. Se emplearon como instrumentos: el cuestionario de Salud MOS SF-36, la Escala Hospitalaria de Ansiedad y Depresión HAD, el cuestionario de Apoyo Social Funcional DUKE-UNK, el Índice de Actividad Lúpica SLEDAI y el Índice de Daño Orgánico SLICC-ACR; y se consideró además el diagnóstico médico de Fibromialgia y de Nefropatía. Los resultados señalaron que factores fisiopatológicos (actividad lúpica y daño orgánico), psicológicos (ansiedad-depresión) y sociodemográficos (ocupación y estado civil) y la interacción entre estos afectan la calidad de vida a nivel mental más que físico en los pacientes con lupus.Palabras clave: Lupus Eritematoso Sistémico, calidad de vida relacionada con la salud, ansiedad, depresión, Fibromialgia. AbstractThe aim of this research was to evaluate the impact of anxiety, depression, social support, Systemic Lupus Erythematosus (SLE) disease activity index, fibromyalgia, organic and kidney damage, and time of diagnosis of disease on Health-related Quality of Life in 78 patients with SLE diagnosis. Participants completed the Health Survey Questionnaire (SF-36), the Hospital Anxiety and Depression (HAD) scale, the Duke-UNK Functional Social Support questionnaire, the SLEDAI (SLE Disease Activity Index), and the SLICC/ACR damage index for SLE. As a complementary measure, Fibromyalgia and Nephropathy diagnosis was considered. The results shown that in patients with lupus, pathophysiological (SLE disease activity index and organic damage), psychological (anxiety-depression) and sociodemographic factors (occupation and civil status) affect the quality of life in the mental domain rather than in the physical level.

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“…The importance of assessing HRQL in patients with chronic pain has been documented by our recent studies of patients with inflammatory rheumatic diseases (RA, psoriatic arthritis and ankylosing spondylitis) (70), systemic lupus erythematosus (81,82), symptomatic knee and hip osteoarthritis (69), postmenopausal women with vertebral fractures (83), and fibromyalgia (59). In comparison with healthy controls, all of the rheumatic conditions significantly impaired all eight health concepts of the SF-36 in both the physical and mental component, but the disease with the worst HRQL for these dimensions was RA (70).…”

Section: Health-related Quality Of Life Assessmentmentioning

confidence: 99%

“…In comparison with healthy controls, all of the rheumatic conditions significantly impaired all eight health concepts of the SF-36 in both the physical and mental component, but the disease with the worst HRQL for these dimensions was RA (70). Overall, the dimensions typically affected in inflammatory rheumatic diseases were physical functioning, limitations due to physical function, and bodily pain, whereas the level of perceived HRQL in patients with fibromyalgia seems to be explained more by their mental health than by their physical condition (59,69,70,(81)(82)(83). A number of pain-related quality of life selfadministered instruments have been constructed to evaluate pain-related functional disturbances in specific diseases or pain conditions in which the patient is asked to list the activities or tasks they regularly performed before the onset of pain but have since found difficult.…”

Section: Health-related Quality Of Life Assessmentmentioning

confidence: 99%

Pain assessment strategies in patients with musculoskeletal conditions

2012

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Valid and reliable assessment of pain is fundamental for both clinical trials and effective pain management. The nature of pain makes objective measurement impossible. Chronic musculoskeletal pain assessment and its impact on physical, emotional and social functions require multidimensional qualitative tools and healthrelated quality of life instruments. The recommendations concerning outcome measurements for pain trials are useful for making routine assessments that should include an evaluation of pain, fatigue, disturbed sleep, physical functioning, emotional functioning, patient global ratings of satisfaction, and quality of life. Despite the growing availability of instruments and theoretical publications related to measuring the various aspects of chronic pain, there is still little agreement and no unified approach has been devised. There is, therefore, still a considerable need for the development of a core set of measurement tools and response criteria, as well as for the development and refinement of the related instruments, standardized assessor training, the cross-cultural adaptation of health status questionnaires, electronic data capture, and the introduction of valid, reliable and responsive standardized quantitative measurement procedures into routine clinical care. This article reviews a selection of the instruments used to assess chronic musculoskeletal pain, including validated newly developed and well-established screening instruments, and discusses their advantages and limitations

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Health-related quality of life in Italian patients with systemic lupus erythematosus. I. Relationship between physical and mental dimension and impact of age

Abstract: Both PCS and MCS contribute to the decrease in HRQOL in SLE patients. In SLE the mutual interaction between these two dimensions seems to be more relevant than in healthy people.

Cited by 82 publications

References 14 publications

Qualidade de vida relacionada à saúde em pacientes com lúpus eritematoso sistêmico no Centro-Oeste do Brasil

Qualidade de vida relacionada à saúde em pacientes com lúpus eritematoso sistêmico no Centro-Oeste do Brasil

Calidad de vida relacionada con la salud, factores psicológicos y fisiopatológicos en pacientes con diagnóstico de Lupus Eritematoso Sistémico - LES

Pain assessment strategies in patients with musculoskeletal conditions

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