Heart rate acceleration and deceleration capacities associated with circadian blood pressure variation

Abstract

Background Heart rate acceleration and deceleration capacities are novel parameters that can quantify sympathetic and vagal modulation. However, how acceleration and deceleration capacities associated with circadian blood pressure (BP) variation remains unknown. Methods A total of 141 patients with essential hypertension were included in our study. Based on the nocturnal decline rate of systolic BP (SBP), patients were divided into two groups, as dippers and nondippers. Baseline demographic characteristics, ambulatory blood pressure monitoring (ABPM) parameters, Holter recordings, and echocardiographic parameters were collected. Results The absolute values of acceleration capacity (AC) (−7.75 [−8.45 ~ −6.3] ms vs. −6.6 [−8.25 ~ −5.2] ms, p = .047) and deceleration capacity (DC) (7.35 [6.1 ~ 8.1] ms vs. 6.3 [5.1 ~ 7.6] ms, p = .042) were significantly higher in dippers than in nondippers. By multivariate logistic regression analysis, left atrial diameter (LAd) was found to be an independent risk factor for nondipper status in acceleration capacity model (odds ratio 1.174, 95% confidence interval 1.019–1.354, p = .027) and deceleration model (odds ratio 1.146, 95% confidence interval 1.003–1.309, p = .045). Sleep SBP was positively correlated to acceleration capacity ( r = .256, p = .002) and negatively correlated to deceleration capacity ( r = −.194, p = .021). Conclusions The absolute values of acceleration capacity and deceleration capacity were higher in patients with dipper hypertension than in patients with nondipper hypertension. However, acceleration and deceleration capacities were not independent risk factors for blunted BP variation. Sleep SBP seemed to be better correlated to the impairment of autonomic nervous system (ANS) function than other ABPM parameters.

The effect of passive lower limb training on heart rate asymmetry

“…The reduction of deceleration capacity may be a sign of hidden cardiovascular disease. Acceleration capacity has been shown to predict dilated cardiomyopathy (Yan et al 2020). In this study, more participants (80%) exhibited short-term asymmetry with SD1 d >SD1 a , which showed consistency with some researches.…”

Heart rate deceleration and acceleration capacities associated with circadian rhythm of blood pressure in essential hypertension

“…LY Yan et al reported that the absolute values of AC and DC were lower in non-dipper hypertension patients than in dipper hypertension patients. However, DC and AC were not identi ed as independent risk factors for BP non-dipper status [17].…”

“…The heart rate deceleration and acceleration capacities were consider as novel HRV index, measured by the Holter system. The following calculation methods were used as previously described [17]: First, heart beat intervals were selected as decelerating anchors when > 1.00 but ≤ 1.05 of the preceding heartbeat interval; heartbeat intervals were selected as accelerating anchors when < 1.00 but ≥ 0.95 of the preceding heartbeat interval. Second, the heartbeat intervals around the decelerating and accelerating anchors were collected.…”

A case report of autoimmune GFAP astrocytopathy presenting with abnormal heart rate variability and blood pressure variability

“…Dipper is thought to be a normal physiological condition. Non-dipper can be produced by autonomic dysfunction and is associated with target organ damage and an increased risk of cardiovascular death [ 15 ]. The CRBP of our case was non-dipper.…”