Heating/Solvent Responsive Shape‐Memory Polymers for Implant Biomedical Devices in Minimally Invasive Surgery: Current Status and Challenge

Xiao, Rui; Huang, Wei Min

doi:10.1002/mabi.202000108

Cited by 87 publications

(67 citation statements)

References 326 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As polymer-based stent, it is invisible under conventional devices like X-rays and ultrasound. [8] We consider to embed two metal grains at both ends of the head and tail of the scaffold as "Marker" when it is printed. This is a simple and practical method which is same as the scaffold that has been put into use, to make the stent visible under X-rays.…”

Section: Synthesis Of the Materialsmentioning

confidence: 99%

“…[4][5][6][7] The unique property of SMP endorsed it to be a good candidate for minimal invasive surgical devices, especially the biodegradable SMPs that could avoid a secondary surgery to retrieve the device. [8] Tailoring the scaffold with shape memory effect (SME) could significantly reduce fraction of frame coverage, lower the possibility of thrombosis, embolism, and attenuate surgical approach injuries by deforming deployment and responsive recovery. Large number of researchers have studied the SMPs stent, besides the SME biocompatibility and biodegradability, [9,10] eliminating adverse reactions such as inflammation caused by exogenous materials is other criterion which also needs to be considered.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

4D Printing of Shape Memory Vascular Stent Based on βCD‐g‐Polycaprolactone

Zhou

Cao

et al. 2021

Macromol. Rapid Commun.

View full text Add to dashboard Cite

The 4D-printing technology is applied to fabricate a shape memory peripheral stent with good biocompatibility, which sustains long-term drug release. The star polymer s-PCL is prepared by ring opening polymerization of -caprolactone with the -OH of -cyclodextrin ( CD) as initiator, and then the s-PCL is modified with acrylate endgroup which allows the polymerization under UV light to form the crosslinking network c-PCL. Attributed to the feature of the high crosslinked structure and chemical nature of polycaprolactone (PCL) and CD, the composite exhibits appropriate tensile strength and sufficient elasticity and bursting pressure, and it is comparable with great saphenous vein in human body. The radial support of the 4D-printed stent is 0.56 ± 0.11 N and is equivalent to that of commercial stent. The cell adhesion and proliferation results show a good biocompatibility of the stent with human umbilical vein endothelial cells. Due to the presence of CD, the wettability and biocompatibility of the materials are improved, and the sustained paclitaxel release based on the host-guest complexion shows the potential of the drug-loaded stent for long-term release. This study provides a new strategy to solve the urgent need of small-diameter scaffolds to treat critical limb ischemia.

show abstract

Section: Synthesis Of the Materialsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

4D Printing of Shape Memory Vascular Stent Based on βCD‐g‐Polycaprolactone

Zhou

Cao

et al. 2021

Macromol. Rapid Commun.

View full text Add to dashboard Cite

show abstract

“…There are excellent reviews which cover this fascinating class of materials (e.g., [1][2][3][4][5][6][7][8][9]). SMPs receive special attention in the biomedical field [1,2,[8][9][10][11][12][13][14]. A few articles discussed potential applications in aerospace technology [15,16].…”

Section: Introductionmentioning

confidence: 99%

A Mechanical Analysis of Chemically Stimulated Linear Shape Memory Polymer Actuation

et al. 2021

View full text Add to dashboard Cite

In the present work, we study the role of programming strain (50% and 100%), end loads (0, 0.5, 1.0, and 1.5 MPa), and chemical environments (acetone, ethanol, and water) on the exploitable stroke of linear shape memory polymer (SMP) actuators made from ESTANE ETE 75DT3 (SMP-E). Dynamic mechanical thermal analysis (DMTA) shows how the uptake of solvents results in a decrease in the glass temperature of the molecular switch component of SMP-E. A novel in situ technique allows studying chemically triggered shape recovery as a function of time. It is found that the velocity of actuation decreases in the order acetone > ethanol > water, while the exploitable strokes show the inverse tendency and increases in the order water > ethanol > acetone. The results are interpreted on the basis of the underlying chemical (how solvents affect thermophysical properties) and micromechanical processes (the phenomenological spring dashpot model of Lethersich type rationalizes the behavior). The study provides initial data which can be used for micromechanical modeling of chemically triggered actuation of SMPs. The results are discussed in the light of underlying chemical and mechanical elementary processes, and areas in need of further work are highlighted.

show abstract

“…1 Additional special shape memory effects (SMEs) including multiple-SME, spatial SME, two-way SME, were included in the several review articles to demonstrate future applications of SMPs, such as biomedical, sport, textile, aerospace, and sensor fields. [2][3][4][5][6][7][8] In the aforementioned thermally active shape memory behavior involving melt-induced contraction (MIC), it was known as the one-way SME (1W-SME). 2 A threedimensional model was successfully developed to simulate the stress-strain behavior in the programming steps and the stress response in the constrained recovery process for the 1W-SME.…”

mentioning

confidence: 99%

Preparation and characterization of two‐way shape memory olefin block copolymer/silicone elastomeric blends

Lai

Chen

2021

J of Applied Polymer Sci

View full text Add to dashboard Cite

Very few olefin block copolymer (OBC)-based shape memory polymers (SMPs) studies were reported in the literature so far. This study investigated the preparation of OBC and silicone elastomeric blends (70/30 and 50/50) using a meltblending technique to form the first two-way OBC-based SMPs, to our best knowledge. Two phr of ((2,5-bis(tert-butylperoxy)-2,5-dimethylhexane (DHBP) was used to prepare flexible OBC/silicone D2 (D2 representing 2 phr of DHBP) networks. DHBP not only assisted the curing of OBC and silicone but also increased their compatibility in the blends. Despite the very low crystallinity of the OBC elastomer component, 10.4%, corresponding to only~7% based on total resins in the OBC/silicone D2 70/30 blend, the rare two-way shape memory behavior at such a low crystallinity was still envisaged. Regarding two-way shape memory results at various loads, both entropy-driven and crystallization-driven contributions to the overall actuation magnitude (R act )were at the highest level under 450 kPa, attributing to the highest orientation of molecular networks in the blends. With increasing the applied stress, the R act of OBC/silicone (70/30) sample increased from 4.1% to 23.7% due to the increased strain-induced crystallization effect confirmed by the XRD (X-ray diffraction) evaluation, while the recovery magnitude (R rec ) was maintained at the high level, close to 90%, without the hindrance of high load on the recovery due to high elasticity of silicone rubber. Besides, the crystallization-driven contribution to the overall actuation magnitude was higher for the blends containing the higher amount of crystalline OBC elastomer in the blends. On behalf of silicone with outstanding thermal stability, high elastic behavior, and high hydrophobicity, OBC/silicone SMP blends with versatile properties could meet different applications.

show abstract

Heating/Solvent Responsive Shape‐Memory Polymers for Implant Biomedical Devices in Minimally Invasive Surgery: Current Status and Challenge

Cited by 87 publications

References 326 publications

4D Printing of Shape Memory Vascular Stent Based on βCD‐g‐Polycaprolactone

4D Printing of Shape Memory Vascular Stent Based on βCD‐g‐Polycaprolactone

A Mechanical Analysis of Chemically Stimulated Linear Shape Memory Polymer Actuation

Preparation and characterization of two‐way shape memory olefin block copolymer/silicone elastomeric blends

Contact Info

Product

Resources

About