Helical and Tubular Lipid Microstructures that are Electroless‐Coated with CoNiReP for Wireless Magnetic Manipulation

Abstract

Hybrid magnetic phospholipidic-based tubular and helical microagents are wirelessly manipulated by means of a 5-DOF electromagnetic system. Two different strategies are used to manipulate these nanostructures in simulated biologic capillaries. Tubules are pulled by applying magnetic field gradients and oriented by magnetic fields. Helices exhibit a cork-screw motion similar to the swimming strategy used by motile bacteria such as E. coli.

Magnetic Helical Microswimmers Functionalized with Lipoplexes for Targeted Gene Delivery

“…[ 6,14 ] In nature, bacteria such as E. coli swim in viscous fl uids by rotating fl agella in a helical wave to propel themselves. [ 15 ] Inspired by this fl agellar propulsion method, magnetic micro-/nanoswimmers with helical shapes have been fabricated by different methods such as glancing angle deposition (GLAD), [ 16 ] self-rolling techniques, [ 17,18 ] 3D lithography, [ 19 ] and biotemplate methods. [ 20 ] Artifi cial bacterial fl agella (ABFs) [ 21 ] are one type of magnetic helical microswimmers with helical shapes and magnetic materials.…”

Preparation and applications of self-assembled natural and synthetic nanostructures

“…10 μA at comparatively lower applied macroscopic electric fields (B60À150 kV/cm) (Tavakkoli et al, 2014;Garcia et al, 2010;Schuerle et al, 2012). These hollow tubules can be aligned magnetically and a composite is formed by recasting them as polymer matrix.…”

Fabric of magnetically actuated microstructure for targeted cell transportation

“…Various types of magnetically actuated microrobots have been developed to realize these specific biomedical applications [2 -6]. Among the various medical microrobots, the function of transportation can be implemented using biocompatible and magnetic materials, such as lipid with CoNiReP helical structures [4], nickel nanowires [5], or helical microswimmers fabricated by 3D laser lithography [6].…”