Helicobacter pylori and its hematological effect

Helicobacter pylori-Related Extraintestinal Manifestations—Myth or Reality

“…Contrarily, another recent study in Egypt pointed out that H. pylori infection was more prevalent in patients with refractory or unexplained iron deficiency anemia, revealing also a significant improvement in hematological parameters in patients receiving iron supplements associated with the standard eradication triple therapy in comparison to those receiving only iron supplements [ 31 ]. Similar findings were also reported by a study in 2018 which showed that H. pylori is involved in iron-deficiency anemia and that the eradication of this infection results in improved blood parameters [ 32 ]. Sabbagh et al also sustained the potential relationship between H. pylori infection and iron deficiency anemia, but at the same time stated that H. pylori might not be the only one involved in this relationship since poverty, poor nutritional status, and poor treatment might also be a cause for this effect [ 33 ].…”

“…Nevertheless, a case report of a 35-yearl-old male with H. pylori infection and vitamin B12 deficiency pointed out that the vitamin B12 level normalized after 1 month of vitamin B12 supplementation and standard triple therapy for H. pylori eradication [ 67 ]. In fact, vitamin B12 deficiency is very common worldwide, accounting for 20–60% of incidences in developing countries and up to 20% in developed ones [ 32 ]. Thus, a recent study performed on adults with H. pylori infection showed a significant association between the presence of this infection and vitamin B12 deficiency [ 32 ].…”

“…In fact, vitamin B12 deficiency is very common worldwide, accounting for 20–60% of incidences in developing countries and up to 20% in developed ones [ 32 ]. Thus, a recent study performed on adults with H. pylori infection showed a significant association between the presence of this infection and vitamin B12 deficiency [ 32 ]. Moreover, Annibale et al [ 73 ] found H. pylori to be the only pathological elements in 57.1% of patients with macrocytic anemia due to vitamin B12 deficiency ( Table 1 ).…”

“…in adults with H. pylori infection → significant association between the presence of this infection and vitamin B12 deficiency [ 32 ]…”

Relationship Between Serum Iron and Characteristics Social Population in Patients With Helicobacter Pylori Infection

“…Cũng trong năm 2019, một nghiên cứu của Yousryeia Abdel Rahman tại Ai Cập [11] thực hiện với nhóm bệnh có độ tuổi trung bình khoảng 44 tuổi và nhóm chứng có số tuổi trung bình là 49 tuổi. Giá trị sắt huyết thanh ở hai nhóm này cũng có sự tương quan thuận khi nồng độ sắt huyết thanh trung bình ở nhóm bệnh thấp hơn ở nhóm chính với tỉ lệ lần lượt là 48,6±29 (µg/dL) và 77,4±11 (µg/dL).…”