Hepatoprotective activity of <i> Trianthema decandra</i> on carbon tetrachloride-induced hepatotoxicity in rats

Cleome viscosa(wild mustard): A review on ethnobotany, phytochemistry, and pharmacology

“…The extract-treated group of rats showed a significant reduction in serum enzyme aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), -glutamyl transpeptidase, and lipid peroxidase and an increase in reduced glutathione (GSH) when compared to the CCl 4 -treated control group. In addition, histopathological observations supported the significant protection of the extract, similar to that of the positive control, silymarin (Sengottuvelu et al, 2007).…”

“…The results demonstrated that the coumarino-lignoids possessed significant immunomodulatory activity. Mali et al (2007) have investigated the crude alcohol and aqueous extracts of the seeds of CV for their proclaimed anthelmintic activity using Pheretima posthuma and Sudhakar et al, 2006;Williams et al, 2003;Samy et al, 1999;Mishra et al, 1991 Antipyretic Whole plant/methanol Devi et al, 2003 Gastroprotective Leaves/methanol Bhamarapravati et al, 2003 Hepatoprotective Seeds/aqueous Sengottuvelu et al, 2007Immunomodulatory Aerial/aqueous, ethanol, coumarino-lignoids Tiwari et al, 2004Bawankule et al, 2007 Mutagenic Seed oil Polasa & Rukmini, 1987 Psychopharmacological Whole plant/methanol Parimala Devi et al, 2004 Ascardia galli as test worms. Various concentrations (10-100 mg/mL) of each extract were tested in the bioassay, which involved the determination of time of paralysis and time of death of the worms.…”

Antidiabetic Activity of Ethanolic Extract of Zaleya decandra in Alloxan-Induced Diabetic Rats

“…The aqueous extract of Trianthema decandra (=Z. decandra) root possesses hepatoprotective activity against carbon-tetrachloride-induced liver damage in rats [9]. The ethanol extract of T. decandra exhibited liver protective effect against carbon-tetrachloride-induced hepatotoxicity and also possessed antioxidant activities [10].…”

Antitumor Activity of Cleome Viscosa Against Ehrlich Ascites Carcinoma (Eac) in Swiss Albino Mice

“…Some triterpinoids and flavonoids are found to have promising anticancer and antioxidant activity. MECV shows the presence of triterpenes and flavonoids which may act as anticancer and antioxidant principles with MECV 29,30 . In our earlier studies, we found that MECV possess hepatoprotective and antioxidant properties 31 .…”

“…It can be also used in treatment of malarial fevers, skin diseases, leprosy and fever due to indigestion, blood disorders and uterine complications 8 . Earlier pharmacological reports of C.viscosa were indicating that it has proved to be act as hepatoprotective 9 , anthelminthic 10 , analgesic 11 , antiinflammatory 12 , antimalarial 13 , immunomodulatory 14,15 , mutagenic 16 . Since it has a number of IJPP VOL 2 ISSUE 2 medicinal properties including free radical scavenging activity.…”