Herbal approach for tuberculosis management: A systematic review

Abstract

Background: Tuberculosis is an airborne infection that causes lung damage, and it is particularly harmful to patients with weakened immune systems or other health problems. Allopathic medications are associated with development of cross resistance or multidrug resistance in diseases such as TB, making treatment more difficult. In this case, Herbal remedies are the most effective in treating this disease. Medicinal plants with antituberculotic qualities provide pharmacists with a new supply of medicine, allowing them to create novel drugs depending on their active constituents or intermediate metabolites. Objective: Many recent studies have shown that ayurvedic medicines can reduce mortality dramatically when administered in such situations because they interact with the body's natural environment. Ayurvedic medicine is growing in popularity due to its low toxicity study and lack of side effects when compared to allopathic treatments. Conclusion: Considering botanical categorization and anti-tubercular action, Anti-tubercular medicinal herbs have been chosen from scientific literature for this review. A primary objective of this study is to highlight antituberculosis plants, their chemical compounds, and their anti-tubercular properties.

Cytotoxic Potential of Bioactive Compounds from Aspergillus flavus, an Endophytic Fungus Isolated from Cynodon dactylon, against Breast Cancer: Experimental and Computational Approach

“…In recent years, the use of phytomedicines for cancer treatment has noticeably increased [45]. Phytomedicines are already used for the successful treatment of many diseases and overcome many harmful adverse effects of the standard methods [46]. Plant derived medicines are also used more and more often in combination therapy with other medicines to reduce adverse effects and to increase the effectiveness of the treatment [47,48].…”

Medicinal Plants as Therapeutic Alternatives to Combat Mycobacterium tuberculosis: A Comprehensive Review

“…Streptomycin sometimes leads to renal damage and vestibular and auditory nerve damage; isoniazid may cause hepatitis; rifampicin causes thrombocytopenia, pain, vomiting, nausea, and hepatitis; pyrazinamide leads to arthralgia and hepatitis; ethambutol may cause neuritis and color blindness; cycloserine results in convulsions, dizziness, depression, and psychotic reactions; ethionamide causes diarrhea, abdominal pain, and hepatotoxicity; and kanamycin may cause vertigo, damage to the auditory nerve, nephrotoxicity, skin rash from thioacetazone, and exfoliative dermatitis [ 63 ]. Researchers are working on alternate medications—phytoproducts—to avoid such side effects.…”

Traditional Medicinal Plants with Significant Protection Against Antitubercular Drug-induced Liver Injury: A Systematic Review

“…The hepatoprotective TMP species were reported from different parts of the plants including leaves, stem, root, aerial, fruits, bulbs, rhizomes, dry peel, seeds, root, tuber, whole plant, flower (petals), shoot and stem bark. From Table 1 the major parts of the plants that were studied were leaves (19 studies), root (9), fruit (8), whole plant (5), The folkloric and pharmacological uses of the plants reported in the literature cited are also summarized in this review. Among the extraction mediums, ethanol, methanol and water were the most frequently used (Table 1).…”