Herbal nano-formulations for topical delivery

Khogta, Saloni; Patel, Jahanvi; Barve, Kalyani; Londhe, Vaishali

doi:10.1016/j.hermed.2019.100300

Cited by 55 publications

(22 citation statements)

References 68 publications

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“…There has been an increasing focus on the drug delivery potential of nano-formulations in the recent years. [80][81][82][83][84] Application of nano formulation strategies on bioactive molecules could increase their solubility, absorption, bioavailability, protect them from degradation, prolong their circulation time in plasma, 82,85 and make them selective biodistribution in the inammatory parts. 86 In addition, the nano formulation strategies could also improve intracellular penetration, reduce systemic toxicity and open up the potential for co-delivery of therapeutic agents.…”

Section: Nano Formulation Strategiesmentioning

confidence: 99%

Anti-rheumatic effect of quercetin and recent developments in nano formulation

et al. 2021

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Section: Nano Formulation Strategiesmentioning

confidence: 99%

Anti-rheumatic effect of quercetin and recent developments in nano formulation

et al. 2021

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“…The structural surface and shape of carriers and the formulation can be easily investigated by transmission electron microscopy [66]. First, the samples should be diluted with distilled water then place a drop on a 200 mesh carbon film covered copper grid and further stained with a suitable staining solution.…”

Section: Transmission Electron Microscopy (Tem)mentioning

confidence: 99%

A review on herbal drug loaded into pharmaceutical carrier techniques and its evaluation process

Sandhiya

Ubaidulla

2020

Futur J Pharm Sci

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Background: The herbal drug is molded in nanocarriers to boost growing interest in a pharmaceutical era for various fields in sort to amplify therapeutic worth. Nowadays, a promising interest has been developed in nanotechnology using herbal medicines as core material to provoke its activity on the target site. Main body: By administering herbal medicine in the nano-size form, there are chances for improving the bioavailability, binding receptor selectivity due to higher active surface energy thereby enhancing the effectiveness and safety of the active entity. In the last few decades, formulations with nano-sized herbal active ingredients have emerged as nano-phytomedicines owing to its wide range of interest and effectiveness because of its unique nature. Nanonized drug delivery structure of herbal drug has an approaching outlook for getting bigger the doings and overcome problems associated with plant medicine. The current review will focus on nanoparticles, herbal drug-loading techniques, herbal nanoformulations, and applications in various fields. Conclusion: We conclude that by formulating herbal drug in nanocarriers would be a promising guide for the progress of core remedy and will act as a promising proposal for many pathological conditions.

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“…While collagens, elastic fibers, sweat glands, hair follicles, connective tissues, touch receptors, blood capillaries exist in the dermis. The hypodermis is the last layer of skin structure, primarily constructed of areolar and adipose tissues and large blood vessels [9,10]. Noteworthily, skin pigmentation/hyperpigmentation is one of the aging processes occurring at the epidermis layer caused by UV-induced radiation.…”

Section: Introductionmentioning

confidence: 99%

“…Surfactants and sometimes co-surfactants used during the nano emulsification step are mostly non-ionic. The rule of thumb, surfactants of a final HLB value between 4-6 are ideal for preparing W/O nanoemulsions, whereas a higher HLB value (8)(9)(10)(11)(12)(13)(14)(15)(16) is suitable for oil-in-water systems.…”

Section: Introductionmentioning

confidence: 99%

The role of bioactive phytoconstituents-loaded nanoemulsions for skin improvement: a review

Romes

Wahab

Hamid

2021

Biotechnology & Biotechnological Equipment

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As the largest organ in the human body, the skin should be protected from various harmful chemicals and pollutants from the surrounding environment and ultraviolet (UVA/UVB) radiation emitted from sunlight. This has prompted formulation scientists to embark on new technology to formulate cosmetics free of synthetic chemicals using natural plant-based extracts as the replacement. Natural phytoanti-oxidants, viz. catechin, quercetin and gallic acid, are polyphenols whose therapeutic values (antioxidative, antityrosinase, antiviral and antimicrobial) are underutilized. Plant-based nanoemulsions offer an efficient and safe topical delivery system for improving the skin and regenerative treatment. The bioavailability of the phytoanti-oxidants for molecular-level skin repair is enhanced by better permeation of the nanoemulsions' nano-sized particles through the stratum corneum. This review highlights several phytoconstituent-containing nanoemulsions and their bioactivities for cosmetic applications. The mechanisms of skin improvement for anti-aging skin are also presented in detail. In short, nanoemulsion technology is a powerful tool for an effective topical delivery system of potent skin-protecting and rejuvenating plant-based extracts. With increasing demand from consumers worldwide for nano-formulated phytohormones or phytoextractives, nanoemulsions will see a new dimension with better future prospects.

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Herbal nano-formulations for topical delivery

Cited by 55 publications

References 68 publications

Anti-rheumatic effect of quercetin and recent developments in nano formulation

Anti-rheumatic effect of quercetin and recent developments in nano formulation

A review on herbal drug loaded into pharmaceutical carrier techniques and its evaluation process

The role of bioactive phytoconstituents-loaded nanoemulsions for skin improvement: a review

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