Herpes gestationis in Mother and Erythemato-Pustulous Rash in the Newborn with Positive Direct Immunofluorescence

Guillet, G.; Nougué, J; Oksman, F

doi:10.1159/000248691

Cited by 8 publications

(2 citation statements)

References 12 publications

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“…The skin lesions may be present at birth or may occur later, until the fifth day of life. 10 In our case, the infant also developed papulovesicular eruptions on the fourth day of life that resolved spontaneously. Two cases of extracutaneous involvement in offspring of mothers with maternal herpes gestationis have been reported.…”

Section: Discussionsupporting

confidence: 50%

A Case Report of Neonatal Convulsions Due to Maternal Herpes Gestationis

et al. 2007

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Section: Discussionsupporting

confidence: 50%

A Case Report of Neonatal Convulsions Due to Maternal Herpes Gestationis

et al. 2007

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“…The literature review identified 51 original cases of neonatal AIBDs from 48 full‐text papers : 46 from the English‐language literature and 5 in other languages, which were translated. There was an increase in the number of reported cases over the decades.…”

Section: Resultsmentioning

confidence: 99%

Neonatal Autoimmune Blistering Disease: A Systematic Review

Zhao

Chiang

Murrell

2016

Pediatric Dermatology

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We aimed to better understand the pathogenesis, clinical features, prognosis, and treatment of neonatal autoimmune blistering diseases (AIBDs). We searched Medline, Embase, PubMed, Latin American and Caribbean Health Sciences Literature, and reference lists of identified articles. Inclusion criteria were articles published from 1946 to December 2014 in any language. Exclusion criteria were age greater than 4 weeks and no confirmed AIBD diagnosis. We identified 51 cases of neonatal AIBDs: 34 cases of pemphigus (31 pemphigus vulgaris [PV], 3 pemphigus foliaceus [PF]) and 17 cases of pemphigoid diseases (9 bullous pemphigoid [BP], 5 linear immunoglobulin A bullous dermatosis [LABD], 1 BP and LABD, 1 epidermolysis bullosa acquisita, 1 bullous systemic lupus erythematosus). Pemphigoid diseases had a higher male predominance (male:female ratio 4.6:1) than pemphigus (male:female ratio 1:1.06) (p = 0.004). Pemphigus had a higher proportion presenting at birth (79.4%) than pemphigoid diseases (29.4%) (p = 0.008). The most common sites involved were the trunk (63.0%), followed by the head and neck (60.9%). The mucosal membranes were involved in 32.6% of cases (27.6% in pemphigus, 41.6% in pemphigoid diseases). Only 33.3% used systemic therapy, and 75.5% achieved control within 3 weeks. Most PV, PF, and BP cases, but not LABDs, reported maternal disease. In pemphigus cases, 75.0% of mothers had active disease and 25.0% were in control. Pregnant women with PV, PF, and PG of any severity can passively transfer autoantibodies leading to neonatal AIBD. Pemphigoid diseases are more likely to present after birth and may be more male predominant. The presentation of LABDs may be different from that of all other AIBDs.

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