Heterotopes Pankreasgewebe in der Gallenblase

Neupert, Gero; Appel, P.; Braun, Susanne; Tonus, Carolin

doi:10.1007/s00104-006-1203-6

Cited by 27 publications

(9 citation statements)

References 13 publications

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“…45% cases of pancreatic ectopic tissue occur in the stomach and duodenum, while 35% occur in the jejunum [ 1 ]. Other very rare locations include gallbladder [ 10 ], mediastinum and even fallopian tube [ 7 , 8 , 11 ]. Commonly used diagnostic modalities for ectopic pancreas include CT scan and endoscopic ultrasound (for upper gastro-intestinal tract).…”

Section: Discussionmentioning

confidence: 99%

“…A complication arising in this location poses unique challenges in diagnosis and treatment for clinicians. Asymptomatic and benign ectopic pancreatic tissues are left alone without therapy [ 10 ]. Once ectopic or herniated pancreatic tissue becomes symptomatic, the presentation and treatment then depends upon its location and type of complication.…”

Section: Discussionmentioning

confidence: 99%

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Pancreas herniation into the mediastinum: a case report

Shafiq

Badshah

et al. 2017

BMC Res Notes

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BackgroundPancreatic tissue found in the mediastinum (both true ectopic and herniated pancreas) is rare. It becomes even more challenging when there are complications associated with this entity.Case presentationWe report an unusual case of pancreatic herniation into the mediastinum in a 90-year-old Caucasian female. This patient initially presented with nausea and vomiting associated with abdominal pain. Serum lipase and amylase both were elevated. Computed tomography scan of the chest, abdomen and pelvis revealed a large hiatal hernia with pancreas herniation into the mediastinum, with superimposed acute pancreatitis likely due to gallstone. Because of its unusual location, the patient also developed acute mediastinitis. The patient was management conservatively and did well. On the day of discharge; she was tolerating a diet, had no pain or nausea and was back to her baseline health.ConclusionAcute pancreatitis can be managed conservatively even if it is in the mediastinum. Also, ectopic or herniated pancreatic tissue is extremely rare and leads to unique clinical presentations, along with diagnostic and therapeutic challenges. Clinicians should not only be vigilant to the presence of ectopic or herniated pancreatic tissue, but also be mindful of the resulting complications.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Pancreas herniation into the mediastinum: a case report

Shafiq

Badshah

et al. 2017

BMC Res Notes

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“…[ 16 ] It has been reported that PET-CT was effective for the detection of NENs and helpful for identification of distant metastasis. [ 18 , 19 ] In our study, 2 patients underwent PET-CT examination which showed adjacent and/or distant metastasis, and the examination results are valuable for preoperatively determining the TNM staging and therapeutic strategy.…”

Section: Discussionmentioning

confidence: 99%

Gallbladder neuroendocrine carcinoma

et al. 2020

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Gallbladder neuroendocrine carcinoma (GB-NEC) is a group of rare and heterogeneous neoplasms and there are few reports at present. We analyzed the clinical and pathological features of 7 patients with GB-NEC who were admitted to Zhejiang Provincial People's Hospital from January 2011 to October 2019. The median age of 7 patients was 58 years with male to female ratio of 1:2.5. Right upper quadrant discomfort was the main complaint and no patients presented carcinoid syndrome-related symptoms. In contrast-enhanced computed tomography (CT) examination, 5 of 6 patients showed well-defined margin and continuous thin line-like contrast enhancement on the mucosa. Among the patients with liver metastases before surgery, 66.7% of patients were cancer antigen 125 (CA-125) positive, and among the patients presented with liver metastases during follow-up period, all patients were CA-125 positive. All patients with elevated CA-125 did not have ascites, ovarian carcinoma, peritoneal carcinoma, and endometrial carcinoma. According to postoperative pathological report, 1 patient was stage IIIA, and the other 6 patients were stage IVB. Six patients underwent surgery, and 1 patient just underwent liver biopsy. Two patients underwent laparoscopic radical cholecystectomy, and neither of them encountered serious complications after surgery with the overall survival time of 4.6 and 16.8 months, respectively. Compared with the patients without chemotherapy, 3 patients postoperatively treated with chemotherapy lived longer. The median survival of all 7 patients was 4.6 months and the 1-, 2-year survival rates were 14.29%, 0%. Surgical resection, including laparoscopic radical cholecystectomy, is feasible for the treatment of advanced GB-NEC in selected patients and has the advantages of prolonging survival in combination with chemotherapy. The elevation of CA-125 can be utilized as an important predictor of poor prognosis, while more investigations are necessary to confirm it.

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“…The first heterotopic pancreatic tissue was described in 1729 by Jean Schultz in the ileal diverticulum and, in 1859, two cases of histologically proven heterotopic pancreatic (HP) tissue were presented by Klob. The first HP case located in the gallbladder was presented by Otschkin in the beginning of the twentieth century [ 1 ]. When the literature was examined, it was seen that there are 34 case reports since 1916.…”

Section: Introductionmentioning

confidence: 99%

A Rare Pathology Mimicking the Gallstone: Heterotopic Pancreas in the Gallbladder

Ferhatoğlu

Kıvılcım

Kartal

et al. 2018

Cureus

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The placement of pancreatic tissue in an organ outside the pancreas is called pancreatic heterotopy. Heterotopic pancreatic (HP) tissue is frequently observed in the stomach and duodenum, while the gallbladder is an extremely rare localization. In this article, we present pancreatic heterotopy located in the gallbladder, a rarely observed embryologic anomaly, with the study of two cases and a review of the literature.

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Heterotopes Pankreasgewebe in der Gallenblase

Cited by 27 publications

References 13 publications

Pancreas herniation into the mediastinum: a case report

Pancreas herniation into the mediastinum: a case report

Gallbladder neuroendocrine carcinoma

A Rare Pathology Mimicking the Gallstone: Heterotopic Pancreas in the Gallbladder

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