High Caloric intake at breakfast vs. dinner differentially influences weight loss of overweight and obese women

Abstract

Objective: Few studies examined the association between time-of-day of nutrient intake and the metabolic syndrome. Our goal was to compare a weight loss diet with high caloric intake during breakfast to an isocaloric diet with high caloric intake at dinner. Design and Methods: Overweight and obese women (BMI 32.4 6 1.8 kg=m 2 ) with metabolic syndrome were randomized into two isocaloric (1400 kcal) weight loss groups, a breakfast (BF) (700 kcal breakfast, 500 kcal lunch, 200 kcal dinner) or a dinner (D) group (200 kcal breakfast, 500 kcal lunch, 700 kcal dinner) for 12 weeks. Results: The BF group showed greater weight loss and waist circumference reduction. Although fasting glucose, insulin, and ghrelin were reduced in both groups, fasting glucose, insulin, and HOMA-IR decreased significantly to a greater extent in the BF group. Mean triglyceride levels decreased by 33.6% in the BF group, but increased by 14.6% in the D group. Oral glucose tolerance test led to a greater decrease of glucose and insulin in the BF group. In response to meal challenges, the overall daily glucose, insulin, ghrelin, and mean hunger scores were significantly lower, whereas mean satiety scores were significantly higher in the BF group. Conclusions: High-calorie breakfast with reduced intake at dinner is beneficial and might be a useful alternative for the management of obesity and metabolic syndrome.

Beneficial effect of high energy intake at lunch rather than dinner on weight loss in healthy obese women in a weight-loss program: a randomized clinical trial

“…The results of the current study on the effect of high energy intake at dinner on weight are in agreement with those of 2 recent interventional studies (24,36) that indicated the favorable effects of early eating throughout the day on weight loss. However, the 2 studies compared a high-energy breakfast with a high-energy dinner (24) or eating breakfast and lunch compared with eating 6 meals/d (36), whereas the current study compared a high-energy lunch with a highenergy dinner.…”

“…However, the 2 studies compared a high-energy breakfast with a high-energy dinner (24) or eating breakfast and lunch compared with eating 6 meals/d (36), whereas the current study compared a high-energy lunch with a highenergy dinner. In addition, the previous studies involved obese and overweight participants with metabolic syndrome and type 2 diabetes, whereas we recruited healthy obese and overweight women.…”

“…Additional evidence indicated that late-lunch eating may have deleterious effects on the success of weight-loss therapy (23). In addition, a recent study on the effects of a high-energy breakfast with reduced intake at dinner showed beneficial results on the management of obesity and metabolic syndrome (24).…”

Is the timing of caloric intake associated with variation in diet-induced thermogenesis and in the metabolic pattern? A randomized cross-over study

“…The timing of meals also influences the success of weight loss strategies: late-lunch eaters lose less weight than 337 early eaters [47]; overweight/obese women lose significantly more weight after a low-calorie dinner weight-338 loss program than after an isocaloric high-calorie dinner program [48]. Therefore, dietary recommendations 339 should probably include indications on the time-of-day for food consumption, besides advice on food quality 340 and quantity.…”

Late-night-dinner is associated with poor glycemic control in people with type 2 diabetes: The KAMOGAWA-DM cohort study

“…It has been reported that late-night-dinner has associated with obesity, metabolic syndrome and hyperglycemia in general population [11][12][13][14]. Besides, it is reported that the risks of metabolic syndrome, diabetes and insulin resistance in the people with having high calorie at dinner were higher than those in the people with having high calorie at breakfast [15]. Another study showed that the evening chronotype was risk of diabetes and metabolic syndromes [16].…”