High incidence of primary gastric lymphoma in northeastern Italy

Doglioni, Claudio; Moschini, A.; Boni, Michele De; Wotherspoon, A.C.; Isaacson, Peter G.

doi:10.1016/0140-6736(92)90280-g

Cited by 267 publications

(134 citation statements)

References 6 publications

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“…In addition, there is considerable evidence that geographical variation exists. Among demographically similar communities in the UK and Italy, large differences in the incidence of gastric lymphoma have been reported (Doglioni et al, 1992). The higher incidence of gastric lymphoma found in Italy was associated with excesses in gastric adenocarcinoma and Helicobacter pylori infection which may be involved in the development of both neoplasms.…”

Section: Discussionmentioning

confidence: 99%

Descriptive epidemiology of gastrointestinal non-Hodgkin’s lymphoma in a population-based registry

1999

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SummaryThe incidence of non-Hodgkin's lymphoma (NHL), particularly at certain extranodal sites, has been demonstrated to be rising, at least in the USA, more than for any other malignancy. One of the major sites of extranodal NHL is the gastrointestinal tract, though little is known of its epidemiological characteristics. Over an 8-year period (1986 to 1993) 1069 primary gastrointestinal NHL cases were reported to the Leukaemia Research Fund Data Collection Survey which covers many parts of England and Wales. Age-standardized incidence rates of gastrointestinal NHL at all sites (0.58/10 5 per year), gastric (0.24/10 5 per year), small bowel (0.17/10 5 per year) and large bowel (0.06/10 5 per year) confirmed that the UK has the lowest rates of gastrointestinal NHL in Europe. An excess of males was observed at all ages and for all sites. Time-trend analyses showed annual increases in incidence rates for gastric (6.3%) and small bowel (5.9%) NHL although a concomitant decrease in gastrointestinal NHL of unknown site suggested that at least part of these increases had resulted from more accurate diagnoses. Overall, the incidence of gastrointestinal NHL significantly increased by 2.7% per annum and was limited to the population aged over 50 years in this series.

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Section: Discussionmentioning

confidence: 99%

Descriptive epidemiology of gastrointestinal non-Hodgkin’s lymphoma in a population-based registry

1999

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“…2,23,24,37 Geographic variations in the prevalence of H. pylori infection, celiac disease, or other environmental factors may be the cause of the difference. 35,38,39 In Middle Eastern countries, the frequency of intestinal lymphoma is high (range, 49 -81%). This may be partly explained by the high prevalence of IPSID in these areas.…”

Section: Discussionmentioning

confidence: 99%

“…Increasing exposure or susceptibility to risk factors, such as H. pylori infection, ultraviolet light, chemicals, and excessive protein or fat in the diet, also may have contributed to this increase. 37,38 In Period C (1993)(1994)(1995)(1996)(1997)(1998)(1999)(2000)(2001)(2002), both the number and the proportion of low-grade B-cell lymphoma increased. This is attributable to an increase in the diagnosis of gastric MALT lymphoma by endoscopy with biopsy.…”

Section: Discussionmentioning

confidence: 99%

Primary gastrointestinal lymphoma in Japan

Nakamura

Matsumoto

Iida

et al. 2003

Cancer

245

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Polymer particle agglomeration and melting causing sheet formation in fluidized bed reactors have been reported to occur during olefin polymerization. The cause of this deleterious sheet formation has not yet been established. Infrared and optical imaging were used to study the temporal temperature and size during polymerization of individual commercially active catalyst particles supported on a nylon mesh. Experiments conducted at 2100 kPa confirmed theoretical predictions that the temporal temperature rapidly attains a maximum after the start of the reaction. The magnitude of the temperature rise increases upon an increase of either reactor temperature, initial catalyst particle diameter, catalyst loading, or addition of hydrogen to the feed. The maximum transient temperature rise of single commercial catalyst particle during ethylene polymerization (7.5°C) is lower than that which can lead to local melting and polymer sheet formation. The temperature rise of particle clusters is much higher than that of individual particles, as the cluster acts as a particle with an effective diameter much larger than that of an individual particle. Thus, to circumvent polymer melting it is essential to avoid catalyst particles clustering, which may be caused by electrostatic attraction. The addition of hydrogen to the feed, often used to control polymer properties, significantly increased the initial particle temperature rise (almost double in some cases). © 2008 American Institute of Chemical Engineers AIChE J, 2008

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“…A strikingly high incidence of gastric lymphoma observed in Northeastern Italy is accom-www.TheOncologist.com panied by a remarkably high prevalence of H. pylori infection [31]. In one case-controlled study, previous H. pylori infection was associated with subsequent development of gastric lymphoma [32].…”

Section: Gastric Malt Lymphomamentioning

confidence: 99%