High-order aberration changes after femtosecond LASIK surgery in patients with high myopia

Feng, Ziqing; Du, Chunyu; Yang, Fan; Li, Xue

doi:10.21037/apm-21-1677

Cited by 12 publications

(7 citation statements)

References 19 publications

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“…Adib-Moghaddam et al [ 12 ] followed up the clinical results 18 months after Trans-PRK and found that corneal spherical aberration and coma were significantly increased after the surgery. Feng et al [ 19 ] found that corneal coma, spherical aberration, and total HOAs were significantly increased at 1 week, 1 month, and 3 months after the surgery compared with the preoperative values. These results were consistent with our report.…”

Section: Discussionmentioning

confidence: 99%

Corneal Asphericity and Higher-Order Aberrations after FS-LASIK and Trans-PRK for Myopia

Wang

et al. 2021

Journal of Ophthalmology

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Objective. To compare the corneal asphericity and higher-order aberrations (HOAs) of femtosecond laser-assisted in situ keratomileusis (FS-LASIK) with Smart Pulse Technology (SPT) assisted transepithelial photorefractive keratectomy (Trans-PRK) for myopia and myopic astigmatism correction. Methods. This prospective study analyzed 88 eyes of 44 patients treated with FS-LASIK and 64 eyes of 32 patients treated with Trans-PRK. All eyes had low to moderate myopia with or without astigmatism (spherical equivalent (SE) <−6.00 diopters). The uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), SE, asphericity (Q value) of the anterior corneal surface, index of surface variance (ISV), corneal higher-order aberrations (HOAs), vertical coma (Z3−1), horizontal coma (Z31), and spherical aberration (Z40) over a 6 mm diameter central corneal zone diameter were evaluated preoperatively and 1, 3, and 6 months postoperatively. Results. At 6 months, the UDVA and SE were −0.14 ± 0.06 and 0.33 ± 0.33D in FS-LASIK and −0.15 ± 0.06 and 0.35 ± 0.37D in Trans-PRK. There was no difference between the two groups in the postoperative UDVA and SE ( P > 0.05 ). After FS-LASIK and Trans-PRK, the Q values in the 6, 7, 8, and 9 mm zones and ISV of the anterior corneal surface significantly increased ( P < 0.001 ). At 1, 3, and 6 months after surgery, corneal HOA, Z3-1, Z31, and Z40 in both groups were significantly increased compared with those before surgery, with statistically significant differences ( P < 0.001 ). At 1, 3, and 6 months after surgery, the Z3−1 of the Trans-PRK group was significantly lower than that of the FS-LASIK group ( P < 0.001 ). ΔHOA and ΔZ40 were dramatically correlated with the ΔQ value for both FS-LASIK and Trans-PRK procedures. The ΔQ was significantly correlated with the preoperative SE, AD, and AD/CCT after both two procedures (all P < 0.001 ). Conclusions. Both FS-LASIK and Trans-PRK caused the anterior corneal surface to become flatter, and the morphology of the corneal surface was irregular. Corneal HOAs were significantly increased after the two procedures. Trans-PRK using SPT introduced less corneal vertical coma than FS-LASIK. Corneal asphericity changes contributed to the corneal aberrations changes following FS-LASIK and Trans-PRK.

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Section: Discussionmentioning

confidence: 99%

Corneal Asphericity and Higher-Order Aberrations after FS-LASIK and Trans-PRK for Myopia

Wang

et al. 2021

Journal of Ophthalmology

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“…Our study showed a statistically signi cant difference in RMS spherical aberration in both groups between the preoperative and postoperative periods. Changes in corneal asphericity caused by corneal epithelial healing and matrix brosis are primarily responsible for increased spherical aberration (31,32). Furthermore, corneal asphericity was signi cantly correlated with the preoperative MRSE (25,33).…”

Section: Discussionmentioning

confidence: 99%

Effect of Preoperative Pupil Offset on Corneal Higher-Order Aberrations after Femtosecond Laser-Assisted In Situ Keratomileusis

Liu

Zhao

Sun

et al. 2022

Preprint

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Background This study aimed to investigate the relationship between multiple higher-order aberrations (HOAs) subgroups and pupil offset, as well as to analyze the factors affecting postoperative corneal HOAs in patients with different degrees of refractive errors. Methods We enrolled 160 patients (316 eyes) aged ≥ 18 years who had undergone femtosecond laser-assisted in situ keratomileusis (FS-LASIK) treatment. Based on the relationship between the preoperative pupil offset and the postoperative ΔHOAs, all patients were divided into two groups: group I (pupil offset ≤ 0.20 mm) and group II (pupil offset > 0.20 mm). All of the eyes had low to high myopia with or without astigmatism (manifest refraction spherical equivalent (MRSE) < -10.00 D). Uncorrected distance visual acuity, corrected distance visual acuity, MRSE, pupil offset, central corneal thickness, corneal HOAs, vertical coma (Z3 − 1), horizontal coma (Z31), spherical aberration (Z40), trefoil 0° (Z33), and trefoil 30° (Z3 − 3) over a 6 mm diameter central corneal zone diameter were evaluated preoperatively and at 1 and 3 months postoperatively. Results Our result revealed significant differences in postoperative corneal total root mean square (RMS) HOAs, RMS vertical coma, RMS horizontal coma, RMS spherical aberration, and RMS trefoil 30° between group I and group Ⅱ. ΔMRSE was found to be an effective factor for ΔRMS HOAs (R2 = 0.383), ΔRMS horizontal coma (R2 = 0.205), and ΔRMS spherical aberration (R2 = 0.397). In group II, multiple linear regression analysis revealed a significant correlation between preoperative pupillary offset and Δtotal RMS HOAs (R2 = 0.461), ΔRMS horizontal coma (R2 = 0.040), and ΔRMS trefoil 30°(R2 = 0.089). The ΔRMS vertical coma effect factor is the Y-component, and the factor influencing ΔRMS spherical aberration was ΔMRSE (R2 = 0.256). Conclusion A small pupil offset was associated with a lower induction of postoperative corneal HOAs. Efforts to optimize centration are critical for improving surgical outcomes in patients with FS-LASIK.

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“…Understanding of the human ocular refractive system is constantly improving with the rapid development of physical optics. In particular, higher order aberration (HOA) has enhanced the study of visual quality [12][13][14] and has become an important index in research on refractive surgery. Spherical-like aberration or LSA is a higher order aberration with significant impact on visual quality.…”

Section: Discussionmentioning

confidence: 99%

Analysis of Asphericity and Corneal Longitudinal Spherical Aberration of 915 Chinese Myopic Adult Eyes

Zhang¹,

Li²,

Zhang³

et al. 2023

OPTH

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To analyze the corneal asphericity, longitudinal spherical aberration (LSA), and related factors in Chinese myopic adult eyes. Methods: This was a retrospective study of myopic adult patients. The corneal asphericity and LSA were measured at 3.0, 4.0, 5.0, 6.0, and 7.0 mm diameter apertures using corneal tomography. Age and refractive power were recorded for correlation analysis. Results: In total, 531 females and 384 males were included. At the above five diameter settings the corneal asphericity values (Q) of the anterior surface were −0.09±0.21, −0.14±0.16, −0.15±0.13, −0.17±0.11, and −0.20±0.11, and those of the posterior surface were 0.23±0.49, 0.06±0.29, −0.01±0.22, −0.07±0.16, and −0.08±0.15, respectively. The anterior corneal LSA values at these diameters were 0.39±0.19, 0.63±0.27, 0.97±0.36, 0.90±0.30, and 0.83±0.29 D, respectively and the whole corneal values were 0.26±0.20, 0.44±0.27, 0.70±0.36, 0.66±0.30, and 0.59±0.28 D, respectively. Corneal asphericity and peripheral LSA showed no or weak correlation with age or spherical equivalent (all r < 0.2). Conclusion: Corneal anterior and posterior Q values in myopia patients are negatively correlated with corneal diameter. Corneal anterior and whole corneal LSA increased significantly with diameter up to 5 mm, then decreased slightly with diameter. Corneal asphericity and peripheral LSA showed very weak or no correlation with age or spherical equivalent. Clinical Trial Registration Number: ChiCTR1800015985.

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High-order aberration changes after femtosecond LASIK surgery in patients with high myopia

Cited by 12 publications

References 19 publications

Corneal Asphericity and Higher-Order Aberrations after FS-LASIK and Trans-PRK for Myopia

Corneal Asphericity and Higher-Order Aberrations after FS-LASIK and Trans-PRK for Myopia

Effect of Preoperative Pupil Offset on Corneal Higher-Order Aberrations after Femtosecond Laser-Assisted In Situ Keratomileusis

Analysis of Asphericity and Corneal Longitudinal Spherical Aberration of 915 Chinese Myopic Adult Eyes

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