Highly efficient photothermal sterilization of water mediated by Prussian blue nanocages

Jiang, Tingting; He, Jiaojie; Sun, Lei; Li, Zhenglin; Wang, Qiao; Sun, Yuxiu; Wang, Wei; Wang, Yuanlin

doi:10.1039/c7en01245d

Cited by 37 publications

(12 citation statements)

References 40 publications

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“…Other literature reported that Prussian blue could kill E. coli 100% within 5 min through the photothermal effect. However, due to its high photothermal conversion rate, Prussian blue may increase the risk of damage to normal tissue ( Jiang et al, 2018 ). Tannic acid is a polyphenolic compound, which is the active ingredient extracted from gallnut ( Ninan et al, 2016 ; Yan et al, 2019 ; Liu et al, 2020 ).…”

Section: Introductionmentioning

confidence: 99%

Triggering Drug Release and Thermal-Disrupting Interface Induced Mitigation of Composite Photothermal Hydrogel Treating Infectious Wounds

Long

Lei

et al. 2021

Front. Bioeng. Biotechnol.

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Introduction: With the development of photothermal technology, the appearance of composite photothermal hydrogels has increased the selectivity of treating infectious skin defects. However, how to design composite photothermal hydrogel with better antibacterial performance, reduce the resistance rate of bacteria, and the damage rate of normal tissue still needs further study.Methods: The Prussian blue and tannic acid were loaded on polyacrylamide hydrogels. Characterization of DLS, Zeta potential, UV absorption spectrum, hydrogel swelling rate, scanning electronic microscopic, drug release profile, photothermal properties, in vitro cytocompatibility, and antibacterial properties. Experiments were measured by skin defect repair, antibacterial detection, and histological staining experiments.Results: The polyacrylamide hydrogel with photothermal effect and controllable release of tannic acid was successfully prepared. The hydrogel has strong light transmittance and adhesion, and the swelling rate can reach 600%, which improves the self-cleaning ability. SEM results showed the porous structure of hydrogels, promoting cell growth. Through photothermal switches, the composite hydrogel represented adjustable and controllable drug release ability. Combined with the synergistic antibacterial effect of tannic acid, this further enhanced the antibacterial ability and reduced the probability of antibiotic resistance. The in vitro and in vivo experiments showed the hydrogel had good biocompatibility and excellent antibacterial properties, which could promote the repair of infectious skin defects in SD rats.Conclusion: We fabricated a hydrogel with a triggering drug release rate, alleviating heat damage, transparent morphology, mechanical stability, strong adhesion, good biocompatibility, and synergistic antibacterial ability, which presents new treatment options for infectious skin defect repair.

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Section: Introductionmentioning

confidence: 99%

Triggering Drug Release and Thermal-Disrupting Interface Induced Mitigation of Composite Photothermal Hydrogel Treating Infectious Wounds

Long

Lei

et al. 2021

Front. Bioeng. Biotechnol.

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“…The optical properties of nanocages were not different, with the usual absorption band centered around All of these papers are oriented towards in vivo applications and to the functionalization of biomedical devices. Yu and colleagues proposed another field of applications for PBNPs, which could have great potential: photothermal sterilization of water [42]. In this case, Prussian blue nanocages were used instead of solid nanoparticles.…”

Section: Photothermal Antibacterial Effect Of Prussian Blue Nanoparticlesmentioning

confidence: 99%

Prussian Blue and Its Analogs as Novel Nanostructured Antibacterial Materials

2021

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Prussian blue is an ancient artificial pigment. Its biocompatibility and the possibility of synthesizing it in nanometric size stimulated the interest of the scientific community. Many uses of Prussian blue nanoparticles have been reported in the field of nanomedicine. More recently, interest into the potential application of Prussian blue nanoparticles as antibacterial agents has spread. Literature regarding Prussian blue and its analogs as antibacterial materials is still limited, but the number of papers has grown quickly over the last 2–3 years.

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“…The self-assembled monolayers demonstrated photothermally induced antibacterial activity against Gram-negative ( E. coli ) and Gram-positive ( S. aureus ) bacterial strains. In order to overcome the NIR laser limits and to irradiate larger areas, the nanocages were used to induce the photothermal sterilization upon solar light irradiation [ 75 ]. In a very recent article, published in 2019, physically cross-linked PVA hydrogel films, containing Prussian blue nanoparticles, displayed a pronounced photothermal effect (up to Δ T ≅ 78 °C) under low NIR laser intensities (0.3 W/cm 2 ) [ 76 ].…”

Section: Reviewmentioning

confidence: 99%

Photothermally active nanoparticles as a promising tool for eliminating bacteria and biofilms

Borzenkov¹,

Pallavicini²,

Taglietti³

et al. 2020

Beilstein J. Nanotechnol.

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Bacterial contamination is a severe issue that affects medical devices, hospital tools and surfaces. When microorganisms adhere to a surface (e.g., medical devices or implants) they can develop into a biofilm, thereby becoming more resistant to conventional biocides and disinfectants. Nanoparticles can be used as an antibacterial agent in medical instruments or as a protective coating in implantable devices. In particular, attention is being drawn to photothermally active nanoparticles that are capable of converting absorbed light into heat. These nanoparticles can efficiently eradicate bacteria and biofilms upon light activation (predominantly near the infrared to near-infrared spectral region) due a rapid and pronounced local temperature increase. By using this approach new, protective, antibacterial surfaces and materials can be developed that can be remotely activated on demand. In this review, we summarize the state-of-the art regarding the application of various photothermally active nanoparticles and their corresponding nanocomposites for the light-triggered eradication of bacteria and biofilms.

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Highly efficient photothermal sterilization of water mediated by Prussian blue nanocages

Abstract: Photothermal sterilization based on PBNs has been demonstrated not only upon NIR irradiation but also most importantly under simulated solar light.

Cited by 37 publications

References 40 publications

Triggering Drug Release and Thermal-Disrupting Interface Induced Mitigation of Composite Photothermal Hydrogel Treating Infectious Wounds

Triggering Drug Release and Thermal-Disrupting Interface Induced Mitigation of Composite Photothermal Hydrogel Treating Infectious Wounds

Prussian Blue and Its Analogs as Novel Nanostructured Antibacterial Materials

Photothermally active nanoparticles as a promising tool for eliminating bacteria and biofilms

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