“…Of the carbon-family members, sp 2 carbon-based materials such as fullerene [4,5], carbon nanotubes [1,[6][7][8][9][10][11], carbon dots [12][13][14], and graphene [15][16][17][18], have been explored for promising applications in biomedicine, including drug delivery, gene transfection, photothermal therapy, photodynamic therapy, biosensing, and even tissue engineering [19][20][21]. For instance, the hollow space in fullerene/carbon nanotubes and large surface-to-volume ratio of graphene can be used for the encapsulation and intracellular delivery of therapeutic agents.…”