Highly selective zeolite-catalysed mono-N-alkylation of arylenediamines by dialkyl carbonates

Synthesis, structural characterization of benzimidazole-functionalized Ni(II) and Hg(II) N-heterocyclic carbene complexes and their applications as efficient catalysts for Friedel–Crafts alkylations

“…The commercially available reagents and solvents were used without further purification unless otherwise noted. Nethylbenzene-1,2-diamine [94], N-(6-methylpyridin)imidazole [95], N-(6-methylpyridin)benzimidazole [95], Ni(PPh 3 ) 2 Cl 2 [96] and b-nitrostyrenes [97] were prepared by using published procedures. Column chromatography was performed with silica gel (200e300 mesh).…”

Imaging of parastomal hernia using three-dimensional intrastomal ultrasonography (Br J Surg 2011: 98: 1026–1029)

“…ortho ‐Nitroaniline can also be used in the place of the 1,2‐diaminoarene under reducing conditions 13. However, the preparation of N‐1‐substituted benzimidazoles using these methods depends on the availability of the requisite 1,2‐diaminoarene or ortho ‐nitroaniline, which are oftentimes difficult to prepare 14. Benzimidazoles unsubstituted at N‐1 such as 1 are more accessible.…”

Au catalyzed synthesis of benzimidazoles from 2-nitroanilines and CO2/H2

“…Benzimidazoles are important intermediates widely applied in the synthesis of pharmaceutical compounds, 17,18 which are generally produced via condensation reactions of 1,2-diaminobenzenes with formic acid or its derivatives (imidates, esters, orthoesters, or nitriles) under strong acidic conditions at high temperatures 19 or under microwave irradiation. 20 Recently, aldehydes instead of carboxylic acids were used to synthesize benzimidazoles in the presence of different oxidants, which made the synthetic routes relatively clean.…”