Histological Structure of the Thyroid Gland in the Newborn

Larroche, Jeanne‐Claudie

doi:10.1159/000240811

Cited by 3 publications

(1 citation statement)

References 9 publications

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“…However, histological results have shown thyroid abnormalities in hypotrophie neonates which died within the first 24 h after birth (11) and in newborn calves dying from diarrhea (20). In a previous study (4), we observed that the plasma levels of hormonal iodine were lower in newborn calves dying from diarrhea than in healthy animals.…”

Section: Introductionmentioning

confidence: 99%

Relationships between Thyroid Function and Pathology of the Newborn Calf

Cabello¹

1980

Neonatology

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The plasma level of hormonal iodine at birth was measured in 28 calves which remained alive and in 13 animals, born in the same herd, which died within the first month of life. The mean value obtained in the first group (9.18 ± 0.88 μg/100 ml) was significantly higher (p < 0 0.025) than the value observed in the second group (5.63 ± 0.32 μg/100 ml). The neonatal changes in the plasma levels of hormonal iodine were observed from birth to 20 days of age in 32 healthy calves and in 36 calves which suffered from diarrhea but survived. It appears that the animals which remained healthy had significantly lower plasma levels of hormonal iodine at birth and at 48 h of age (respectively, 9.12 ± 1.14 and 6.03 ± 0.42 μg/100 ml) than those measured in the calves which became ill but survived (respectively, 16.18 ± 1.05 μg/100ml, p < 0.001, and 8.11 ± 0.43 μg/100ml, p < 0.005). No significant difference remained after this age. Measurements of the plasma levels of triiodothyronine and of the free-thyroxine index confirmed that the animals which were to become ill were in a hyperthyroid state at birth. We observed a negative correlation (p < 5%) between the plasma levels of hormonal iodine and of thyreostimulin at birth. These results suggest that thyroid dysfunction at birth could be associated with neonatal pathology in the calf, but that morbidity and mortality could not be associated with the same dysfunction. The possible relationships between thyroid function and the pathology of the newborn calf are discussed in the light of experimental results that we have obtained.

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Section: Introductionmentioning

confidence: 99%

Relationships between Thyroid Function and Pathology of the Newborn Calf

Cabello¹

1980

Neonatology

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Non-iatrogenic pathology of the preterm infant

Bendon

Coventry

2004

Seminars in Neonatology

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Transient Hyperintensity of the Infant Thyroid Gland on T1-Weighted MR Imaging: Correlation with Postnatal Age, Gestational Age, and Signal Intensity of the Pituitary Gland

Maki

Nakagawa

Kagaya

et al. 2021

AJNR Am J Neuroradiol

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BACKGROUND AND PURPOSE:The signal intensity of the thyroid in neonates is high on T1WI. It is affected by gestational and postnatal ages. However, the extent of the influence of these ages is unknown. This study investigated the relationship of signal intensities of the infant thyroid with postnatal and gestational ages and anterior pituitary using 3D gradient-echo T1WI. MATERIALS AND METHODS:This retrospective study included 183 T1-weighted images from 181 infants. Using a multiple linear regression analysis, we evaluated the effects of postnatal and gestational ages on the thyroid-muscle signal intensity ratio. The relationship between the thyroid and anterior pituitary signal intensities on T1WI and the age of the infants was evaluated.RESULTS: Multiple linear regression analysis showed that the thyroid signal intensity was affected negatively by postnatal age at examination and positively by gestational age at birth (P , .01 and P ¼ .04, respectively). According to the standardized partial regression coefficients, the influence of postnatal age at examination was stronger than that of gestational age at birth (À0.72 and 0.13, respectively). The thyroid and anterior pituitary signal intensities reached constant values at 12 weeks' postnatal age, and the mean thyroid-anterior pituitary signal intensity ratios were almost 1 throughout the entire period. CONCLUSIONS:The signal intensity of the infant thyroid on T1WI was more strongly influenced by the postnatal age at examination than the gestational age at birth, and it was almost equal to that of the anterior pituitary.

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Histological Structure of the Thyroid Gland in the Newborn

Cited by 3 publications

References 9 publications

Relationships between Thyroid Function and Pathology of the Newborn Calf

Relationships between Thyroid Function and Pathology of the Newborn Calf

Non-iatrogenic pathology of the preterm infant

Transient Hyperintensity of the Infant Thyroid Gland on T1-Weighted MR Imaging: Correlation with Postnatal Age, Gestational Age, and Signal Intensity of the Pituitary Gland

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