Histopathological spectrum of Nephrectomy specimen in a tertiary care centre: with an emphasis on Chronic Pyelonephritis

K, Shanmugasamy; Rajvaithy, Anand; K, Venkatraman; Kotasthane, Dhananjay Shrikant

doi:10.21276/apalm.1547

Cited by 6 publications

(6 citation statements)

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“…Most common cause is obstructive uropathy due to stricture or calculi, which leads to reflux of the infected urine into the renal pelvis. Calcium oxalate stones are the most common renal calculi seen which occurs due to consumption of hard water and supersaturation of calcium oxalate in the urine [10]. In our study, renal stones were present in two cases and two patients had underlying disseminated tuberculosis.…”

Section: Discussionsupporting

confidence: 45%

Histopathological audit of nephrectomy specimens from a single center in North India

Bansal¹,

Jindal²,

Gupta³

2020

Eastern J Med Sci

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Introduction: Nephrectomy is a common surgical procedure for wide variety of renal diseases, including both benign and malignant conditions. The causes of nephrectomy may vary with different geographical areas and institutions. A thorough histopathological analysis of nephrectomy specimens abets formulation of treatment guidelines specific to the geographic area. Objective: The objective of the study was to analyze trends and patterns of renal diseases requiring nephrectomy and to observe variations from the conventional pattern or geographic variation, if any. Methods: A hospital-based study was carried out to study and analyze histopathology of 38 nephrectomies done during the period of 2 years (

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Section: Discussionsupporting

confidence: 45%

Histopathological audit of nephrectomy specimens from a single center in North India

Bansal¹,

Jindal²,

Gupta³

2020

Eastern J Med Sci

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“…In age group of 41-60 years 51-60 years maximum number of cases were found. Kathirvelu S et al [11] are also documented similar observation in their earlier study where they also found in the age group of 51-60 years maximum cases were seen.…”

Section: Discussionsupporting

confidence: 78%

Observational Histopathological Analysis of Renal Lesions in Nephrectomy Specimens

Kumari¹,

Subhadarsini²,

Pandey³

2021

Int J Res Rev

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Aim: This observational retrospective study was initiated to perform histopathological spectrum analysis of renal lesions from resected nephrectomy specimens. Materials and Methods: This was a retrospective observational study. Over a span of 4 years a total of 62 nephrectomy cases who underwent nephrectomy in a tertiary health care center and specimens were received from the surgical Department of the Hospital were analysed. Microscopic and gross features of the specimen were studied. Result: 12(19%) nephrectomy specimens out of 62 were malignant and 50 (81%) were benign. The mean age of patients from whom specimen were collected was 44.16 ± 29.8 years. 34 (54.9%) were Chronic Pyelonephritis cases, some associated with hydronephrosis and others with calculi. Out of 12 total malignant lesions 8 cases (12.9%) constituted as renal cell carcinoma. Among children commonest malignant tumour was Wilm’s tumour. Among the clinical presentation most common was flank pain in 17 (53.1%) cases followed by fever and burning micturition. Conclusion: In current study as compared to the benign tumours, malignant renal tumours far outnumbered. In paediatric age group most common malignancy was the Wilms tumour. Most common histomorphological diagnosis was Chronic Pyelonephritis and among the malignant lesions commonest were Renal Cell Carcinoma. Keywords: Nephrectomy, Histopathology, Chronic Pyelonephritis, Wilm’s tumour, Renal Cell Carcinoma.

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“…This was in concordance with studies by Ashima N Amin (51.6%) and Madhu Kumar et al, (58.33%) and Kulkarni et al [17][18][19] The most common clinical presentation in patients undergoing nephrectomy was found to be flank pain which is consistent with other studies like Aiman et 12,20,24 The incidence of stone( renal and ureteric) was 55% which was much higher as compared to studies done by shanmugasamy. 2 Non neoplastic lesions requiring nephrectomy were more common were males (2:1). This was consistent with studies done by Shanmugasamy et al, Suryawanshi et al 2,14 However some cases of Xanthogranulomatous Pyelonephritis showed a slight female preponderance(1:2) which was similar to studies done by Aiman et al, (1:1.6), Sreedhar et al (1:3), Shaila (100% female).…”

Section: Discussionmentioning

confidence: 99%

“…2 Non neoplastic lesions requiring nephrectomy were more common were males (2:1). This was consistent with studies done by Shanmugasamy et al, Suryawanshi et al 2,14 However some cases of Xanthogranulomatous Pyelonephritis showed a slight female preponderance(1:2) which was similar to studies done by Aiman et al, (1:1.6), Sreedhar et al (1:3), Shaila (100% female). 12,20,25 Malignant tumours (96.4%) compromised most of the renal neoplastic lesions requiring nephrectomy.…”

Section: Discussionmentioning

confidence: 99%

“…An indication of nephrectomy depends on a number of factors like type of lesion, extent of damage, health of the patient and condition of the contralateral kidney. 2 Simple nephrectomy is indicated in patients with irreversibly damaged non-functioning kidney resulting from different benign pathological conditions including severe traumatic injury, obstruction due to stone impacted in kidney or ureter, symptomatic renal infections, renovascular hypertension due to non-correctable renal artery abnormalities or severe unilateral parenchymal damage caused by nephrosclerosis, pyelonephritis, reflux or congenital cystic dysplasia of the kidney. 3 collecting system and renal parenchyma peaks with different age groups-infancy and early childhood, women of childbearing age, and both men and women older than 60 years of age.…”

Section: Introductionmentioning

confidence: 99%

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Study of histomorphological spectrum of lesions in nephrectomy specimen in a tertiary care hospital in South Gujarat

Bajaj¹,

Hathila²

2020

Int J Res Med Sci

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Background: Nephrectomy is a standard surgical procedure in urology indicated in patients with organ confined renal malignancies and irreversible kidney damage resulting from chronic infection, trauma, obstruction and congenital malformation. This study aims to study the histomorphological features of lesions in nephrectomy specimens in a tertiary care hospital, to analyse the neoplastic and non-neoplastic lesions of kidney according to age, gender and site and observe any variation from the conventional pattern.Methods: The present study was conducted in department of pathology, Tertiary care hospital over a period of 5 years and 7 months (1 Jan 2013 to July 31, 2018). This included 4 years retrospective and 1 year 7 months prospective. A total of 73 cases of were studied.Results: Males constituted 65.73% and females constituted 35.27% of all nephrectomy cases. Right kidney was more commonly affected. Highest percentage of patients belonged to 41-50 years age group. 45 cases were of non-neoplastic lesions and 28 cases were of neoplastic lesions. Among neoplastic lesions, one case was benign while remaining 27 cases were malignant. Chronic Pyelonephritis was the most common indication overall and also amongst non-neoplastic lesions with stone identified in 55% cases. Most common neoplastic lesion in nephrectomy specimen was Renal Cell carcinoma (71.4.1%) followed by Wilms tumour (14%).Conclusions: This study gives a fair insight of the current state of incidence of neoplastic and non-neoplastic lesions of kidney requiring surgical intervention.

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Histopathological spectrum of Nephrectomy specimen in a tertiary care centre: with an emphasis on Chronic Pyelonephritis

Cited by 6 publications

References 5 publications

Histopathological audit of nephrectomy specimens from a single center in North India

Histopathological audit of nephrectomy specimens from a single center in North India

Observational Histopathological Analysis of Renal Lesions in Nephrectomy Specimens

Study of histomorphological spectrum of lesions in nephrectomy specimen in a tertiary care hospital in South Gujarat

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