Histopathological Study of Cervical Cancer Specimen at the University of Calabar Teaching Hospital, Calabar

Irabor, Godstime I.; Omotoso, Ayodele; Isiwele, Edoise M.; Nnoli, Martin; Omoruyi, Kenneth A.

doi:10.26838/medrech.2017.4.6.361

Cited by 3 publications

(3 citation statements)

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“…Nigeria is among the countries with a high burden of viral hepatitis with a Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) prevalence of 11% and 2.2%, respectively [28]. This study revealed that majority of the scavengers in the study are in the age bracket 21-30 years which is 45.4% that is in agreement with Irabor et al [29] which concluded that the highest population of scavengers i.e., 36% are in the age bracket 20 - 29 years and Isaac et al [30] stated that majority 35.42% of respondents are between 18-28 years. In terms of education, majority of wastes scavengers in Kwara state all to the category of primary school leavers as the constitute 38.8% of total respondents and closely followed by those without any formal education which constitute 28.3%.…”

Section: Discussionsupporting

confidence: 88%

Incidence of Hepatitis B and C Viruses Among the Scavengers in Kwara State, Nigeria

Raufu

Olayinka

Olawale

et al. 2022

Preprint

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Background. Poor economic situations in developing nations had made scavenging a means of livelihood for millions of youth and women across the globe. Lack of proper source segregation of wastes in developing countries has increased the potential for the transmission of pathogens like Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV). Objectives. This study addressed issues relating to waste scavenging, the potential risk in waste scavenging work and seroprevalence of Hepatitis B and C Virus and its relationship with wastes scavenging among wastes scavengers in Kwara State. Methods. A cross-sectional study was conducted among the scavengers working for major scrap dealers in the three senatorial districts of Kwara State. Consequently, to accomplish the objectives, both primary and secondary data sources were used. The primary data were collected via questionnaires, interviews, blood test and field observations. Whereas the secondary data were extracted from different published and unpublished materials. 240 respondents were administered with questionnaires and undergone hepatitis surface antigen test for both hepatitis B and C in nine of the sixteen local government area in the state. The data were analyzed using statistical package for social science (SPSS version 23) for descriptive and inferential at 5% level of significance. The prevalence of an HBV and HCV infection biological markers (HBsAg and HCsAg) and their associations with exposure to bio-medical waste, socio-demographic factors, and history of occupational injuries was examined. Results. The seroprevalence of HBV and HCV infection among the scavengers were found to be 8.3% and 5% respectively indicating that scavengers are at risk of HBV and HCV infection. Conclusions. It was discovered that there are incidences of Hepatitis B and C virus co-infection among scavengers. Also, awareness and compliance to the usage of PPE was found to be an important factor for protection scavengers against the virus. Therefore, vaccination against HBV, enforcement of usage of PPE, good hygiene practices, regular trainings on occupational safety, proper monitoring by regulatory agency and inclusion of scavengers in mandatory health insurance scheme will help to control risk of HBV and HCV infection among scavengers.

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Section: Discussionsupporting

confidence: 88%

Incidence of Hepatitis B and C Viruses Among the Scavengers in Kwara State, Nigeria

Raufu

Olayinka

Olawale

et al. 2022

Preprint

View full text Add to dashboard Cite

show abstract

“…Nigeria is among the countries with a high burden of viral hepatitis with a HBV and hepatitis C Virus (HCV) prevalence of 11% and 2.2%, respectively [28]. This study revealed that majority of the scavengers in the study are in the age bracket 21-30 years which is 45.4% that is in agreement with Irabor et al [29] which concluded that the highest population of scavengers i.e., 36% are in the age bracket 20 -29 years and Isaac et al [30] stated that majority 35.42% of respondents are between 18-28 years. In terms of education, majority of wastes scavengers in Kwara state all to the category of primary school leavers as the constitute 38.8% of total respondents and closely followed by those without any formal education which constitute 28.3%.…”

Section: Discussionsupporting

confidence: 86%

Incidence of hepatitis B and C viruses among the scavengers in Kwara State, Nigeria

Raimi

Raufu

Olayinka

2022

Microbes and Infectious Diseases

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“…In 1842, the Rigoni Stern and colleagues mentioned that cervical cancer and genital warts in women were associated with sexual contacts but the contagious nature of genital warts were not recognized until 1907 when Ciuffo observed the transmission of warts using cell-free extracts. [23][24][25] Based on the consistency of their association with cervical and anal cancer, the high-risk strains HPV-16, HPV-18, HPV-31, and HPV-45 are also found in these cancers. 26 HPV virus does not have a polymerase gene so the replication of the viral genome depends on the stimulation of cellular DNA synthesis.…”

Section: The Role Of Dna Viruses In Human Cancermentioning

confidence: 99%

The Role of DNA Viruses in Human Cancer

2023

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This review discusses the possible involvement of infections-associated cancers in humans, with virus infections contributing 15% to 20% of total cancer cases in humans. DNA virus encoded proteins interact with host cellular signaling pathways and control proliferation, cell death and genomic integrity viral oncoproteins are known to bind cellular Deubiquitinates (DUBs) such as cyclindromatosis tumor suppressor, ubiquitin-specific proteases 7, 11, 15 and 20, and A-20 to improve their intracellular stability and cellular signaling pathways and finally transformation. Human papillomaviruses (cervical carcinoma, oral cancer and laryngeal cancer); human polyomaviruses (mesotheliomas, brain tumors); Epstein-Barr virus (B-cell lymphoproliferative diseases and nasopharyngeal carcinoma); Kaposi’s Sarcoma Herpesvirus (Kaposi’s Sarcoma and primary effusion lymphomas); hepatitis B (hepatocellular carcinoma (HCC)) cause up to 20% of malignancies around the world.

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Histopathological Study of Cervical Cancer Specimen at the University of Calabar Teaching Hospital, Calabar

Cited by 3 publications

References 0 publications

Incidence of Hepatitis B and C Viruses Among the Scavengers in Kwara State, Nigeria

Incidence of Hepatitis B and C Viruses Among the Scavengers in Kwara State, Nigeria

Incidence of hepatitis B and C viruses among the scavengers in Kwara State, Nigeria

The Role of DNA Viruses in Human Cancer

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