Modern Cryosurgery for Cancer 2012
DOI: 10.1142/9789814329668_0001
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History of Cryosurgery

Abstract: Cryosurgery is an old as well as new technique, and has gone through a long-term process of development. The history of "modern" cryosurgery is relatively short and is closely intertwined with developments in low-temperature physics, engineering, and instrumentation that were made during the last century.• The cryosurgical probes developed in the 1960s allow precise application of cryosurgical treatment deep in the body. This unique ability makes cryosurgery very promising and has resulted in the expansion of … Show more

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Cited by 3 publications
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“… 21 James Arnott described the multiple benefits of local cold application to treat headaches and neuralgia, and together with John Bennet, who believed and pioneered that cold application could retard the advancement of cancerous growth, described the therapeutic benefits of applying cold in external cancers. 22 , 23 Hypothermia was also used by William Osler, who decreased the mortality rate of patients with typhoid from 24.2% to 7.1% at the Johns Hopkins Hospital by using body cooling regimens. 20 …”
Section: Therapeutic Application Of Cold Through Historymentioning
confidence: 99%
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“… 21 James Arnott described the multiple benefits of local cold application to treat headaches and neuralgia, and together with John Bennet, who believed and pioneered that cold application could retard the advancement of cancerous growth, described the therapeutic benefits of applying cold in external cancers. 22 , 23 Hypothermia was also used by William Osler, who decreased the mortality rate of patients with typhoid from 24.2% to 7.1% at the Johns Hopkins Hospital by using body cooling regimens. 20 …”
Section: Therapeutic Application Of Cold Through Historymentioning
confidence: 99%
“…In 1845, Dr. James Arnott believed that certain diseases that had been shown to resist conventional methods, such as cancer, were “ not necessarily fatal or incurable by the powers of Nature or Art .” 22 By these means, he employed congelation (−18°C to −24°C) (later known as cryotherapy ) by applying iced salt solutions to freeze advanced breast and uterine cervix cancers; strikingly, he reported tumor regression and pain amelioration, stating that “congelation arresting the accompanying inflammation, and destroying the vitality of the cancer cell, is not only calculated to prolong life for a great period but may also, not improbably, in the early stages of the disease, exert a curative action . ” 23 Moreover, he observed that pain relief upon local congelation was more efficient than the use of opium, and presented fewer side effects, which led him to continue his studies on the anesthetic properties of cold and refrigeration anesthesia. 22 , 23 In the 19 th century, upon liquefying gases such as oxygen (−182.9°C), nitrogen (−196°C), and hydrogen, cryogen agents arose for therapeutic purposes, mainly to treat skin diseases such as small skin cancers, pigmented nevi, lupus, and epitheliomas.…”
Section: Therapeutic Application Of Cold In Cancer Treatmentmentioning
confidence: 99%
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