HIV prevalence among 338,432 infertile individuals in Hunan, China, 2012-2018: A cross-sectional study

Abstract

Background The prevalence of human immunodeficiency virus (HIV) varies markedly among different risk groups in China, spreading fromhigh-risk populations to the general population. Indeed, China is in a critical period of HIV/acquired immunodeficiency syndrome (AIDS) prevention and control; however, data regarding HIV testing, infection and coinfection among infertile couples are lacking. This study aimed to estimate the HIV/AIDS prevalence to identify risk factors among infertile couples in Hunan, China. Methods A cross-sectional hospital-based study was conducted to evaluate the prevalence of HIV/ other infections (hepatitis B virus (HBV), hepatitis C virus (HCV), syphilis, and Chlamydia trachomatis, Neisseria gonorrhoeae, and Mycoplasma genitalium (MG) infections) among 338,432 infertile individuals in Hunan, China, from 2012 to 2018. We calculated linear trends in prevalence using bivariate linear regression. Results The overall prevalence rates of HIV, chlamydia, gonorrhea, MG, syphilis, and HBV and HCV antibody positivity in this study were 0.04%, 1.73%, 0.05%, 2.60%, 2.15%, 12.01% and 0.56%, respectively. The predominant infection was HBV, followed by MG, syphilis, and chlamydia. Only 1.13% of the participants (382/338432) reported sexually transmitted disease (STD) signs and symptoms suggesting genital tract infection. However, from 2012-2018, the variation in HIV prevalence was not significant (β = 0.000, P TREND = 0.907). The characteristics of the HIV-infected infertile population have not shifted dramatically, with women accounting for 32.56% of HIV cases in China. Overall, 87.60% of HIV-infected individuals have a relatively low education. In total, 37.98% of HIV-positive patients engage in high-risk behaviors.

Influence of alcohol abuse and / or HIV infection on morpho-functional condition of the uterine tube in women of reproductive age

“…Changes in morphometric parameters (length of the ampullary department, outer diameter of the tube at the junction of the isthmus in the ampullary department, the area of the lumen of the ampullary department) can cause severe complications of inflammation or lead to ectopic pregnancy. The study of the epithelial and muscular layer revealed destructivesclerotic changes, which consist in reducing the height of the epithelium and increasing the proportion of connective tissue in the muscular layer of the tube [11,12].…”

Application of ‘CDC- Public security bureau-NGO’ Joint Prevention and Control Mechanism Allied AIDS Prevention and Control in Guangxi, China

“…Acquired immune de ciency syndrome (AIDS) is a highly infectious disease caused by the human immunode ciency virus (HIV). According to the 2019 data, 151,250 new cases of HIV infections were reported in China, with sexual transmission accounting for 97.1% of cases and heterosexual transmission accounting for 73.8% of cases [1][2][3]. Unprotected sex is the main cause of AIDS transmission.…”

Spatial−temporal analysis of HIV/AIDS and syphilis in mainland China from 2007 to 2017

“…Some previous studies indicated that HIV/AIDS and syphilis prevalence have been increasing in the past decades. [11][12][13][14][15] The study from Ye et al 12 predicted incidence rates of AIDS and syphilis to keep increasing over time. Regional and age difference in the prevalence of HIV/AIDS 14 are also reported.…”