Hodgkin’s lymphoma of the mandibular condyle: Report of a case

Ishimaru, Takanori; Hayatsu, Yoshikazu; Ueyama, Yoshiya; Shinozaki, Fumihiko

doi:10.1016/j.joms.2004.06.050

Cited by 8 publications

(6 citation statements)

References 10 publications

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“…Hodgkin’s lymphoma occurs mainly in the lymph nodes (>90%) [ 2 ] and only 1–4% of the cases involve extranodal areas [ 3 – 4 ], appearing as a nodal disease with predilection for neck and mediastinal nodes [ 2 , 5 – 7 ]. Hodgkin’s lymphoma is diagnosed when the histopathological examination shows the presence of Reed-Sternberg cells [ 8 ] which are binucleate cells with a generally abundant cytoplasm and two large nucleoli (one in each core) that appear like ‘owl eyes’. Hodgkin’s lymphoma can be further classified as classic HL or lymphocyte-predominant HL with respective incidences of 95% and 5%.…”

Section: Introductionmentioning

confidence: 99%

Oral manifestations of lymphoma: a systematic review

Silva¹,

Ferreira²,

Leite³

et al. 2016

ecancer

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Lymphoma is a malignant disease with two forms: Hodgkin’s lymphoma (HL) and non-Hodgkin’s lymphoma (NHL). Non-Hodgkin’s lymphoma is diagnosed in extranodal sites in 40% of cases, and the head and neck region is the second most affected, with an incidence of 11–33%, while HL has a very low incidence in extranodal sites (1–4%). The aim of this study was to identify the oral manifestations of lymphoma through a systematic literature review, which we conducted using the PubMed, Lilacs, Embase, and Cochrane Library databases. We found 1456 articles, from which we selected 73. Among the intraoral findings, the most frequent were ulcerations, pain, swelling, and tooth mobility, while the extraoral findings included facial asymmetry and cervical, submandibular, and submental lymphadenopathy. Among the few studies reporting imaging findings, the most cited lesions included hypodense lesions with diffuse boundaries, bone resorptions, and tooth displacements. The publications reviewed highlight gaps in the areas of early detection, diagnosis, and proper treatment.

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Section: Introductionmentioning

confidence: 99%

Oral manifestations of lymphoma: a systematic review

Silva¹,

Ferreira²,

Leite³

et al. 2016

ecancer

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“…Wood and Coltman in 1973 estimated that the incidence of Hodgkin's lymphoma limited to an extranodal site is 0.25% of the overall incidence of Hodgkin's disease. Through a comprehensive review of the literature, we have identified a total of 36 cases of extranodal oral Hodgkin's lymphoma; of these cases, 11 were cases involving the palate or maxilla (excluding the tonsils). Finally, 4 cases of these 11 cases identified were presentations of primary (Stage I) extranodal oral Hodgkin's lymphoma originating from the palatal or maxillary soft tissues.…”

Section: Discussionmentioning

confidence: 99%

A rare case of extranodal Hodgkin's lymphoma of the palate

Kaur

Newlands

2018

Oral Surgery

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Intraoral extranodal Hodgkin's lymphoma is rare. We present the case of a 66‐year‐old gentleman who was treated for necrotizing ulcerative gingivitis of the UR6 tooth by his dentist which failed to resolve. Biopsy and histopathology revealed that this was, in fact, a rare presentation of primary (Stage I) extranodal oral Hodgkin's lymphoma. We present this case, and a review of the relevant literature.

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“…Hodgkin lymphoma, whether primary or relapsed, is rare in the oral soft tissues and jaws. We could trace only 12 reports of primary Hodgkin lymphoma occurring in the oral mucosa, [8,9,[13][14][15][16][17][18][19][20][21] and only a few occurring in the jaws [1][2][3][4][5][6]. Disseminated Hodgkin lymphoma involving the oral mucosa is said to be more common than primary lesions, however, we could trace only a few reports, citing 5 cases, involving the tongue, palate and tonsil [7][8][9][10].…”

Section: Discussionmentioning

confidence: 99%

“…Hodgkin lymphoma, whether primary or relapsed, is rare in the oral soft tissues and jaws [1][2][3][4][5][6]. Although disseminated Hodgkin lymphoma involving the oral mucosa is said to be more common, we could trace only a few reports, citing 5 cases, involving the tongue, palate and tonsil [7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%