How delivery mode and feeding can shape the bacterial community in the infant gut

Song, Se Jin; Domínguez-Bello, María Gloria; Knight, Rob

doi:10.1503/cmaj.130147

Cited by 56 publications

(41 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, microbial colonization of the human infant may begin earlier. The dogma of sterile intrauterine environment has recently been challenged by reports on detection of diverse microbes in placenta, umbilical cord, amniotic fluid, and meconium (3)(4)(5)(6)(7)(8)(9)(10). Taking these preliminary observations together, the contact with the complex bacterial communities is clearly already initiated in utero and the impact of maternal microbiota may be more important than we had previously believed.…”

Section: Microbial Exposure In Uteromentioning

confidence: 89%

“…Recently, more attention has been given to differences in early microbial contact related to the mode of birth. An accumulating body of evidence indicates that vaginally and surgically delivered neonates exhibit distinct gut colonization patterns (6,7,33,44,45). The differences in gut microbiota composition may still be observed at the age of 7 y (46).…”

Section: Mode Of Deliverymentioning

confidence: 99%

See 1 more Smart Citation

Gut microbiota: a source of novel tools to reduce the risk of human disease?

et al. 2014

View full text Add to dashboard Cite

Section: Microbial Exposure In Uteromentioning

confidence: 89%

Section: Mode Of Deliverymentioning

confidence: 99%

Gut microbiota: a source of novel tools to reduce the risk of human disease?

et al. 2014

View full text Add to dashboard Cite

“…Specifically, mode of birth (vaginal delivery vs C-section) plays a significant role in seeding the infant microbiome, with transference of taxa to the infant from maternal vaginal and gut microbiomes in the case of vaginal birth, and skin and environmental microbes in the case of C-sections [27, 28•, 29, 30]. While this results in a significant difference in early microbiome structure, particularly with reduced species richness among C-section infants, the long-term implications are still unknown [31].…”

Section: Role Of the Microbiome In Human Biology And Evolutionmentioning

confidence: 99%

Insights into human evolution from ancient and contemporary microbiome studies

Schnorr

Sankaranarayanan

Lewis

et al. 2016

Current Opinion in Genetics & Development

View full text Add to dashboard Cite

Over the past decade, human microbiome research has energized the study of human evolution through a complete shift in our understanding of what it means to be human. The microbiome plays a pivotal role in human biology, performing key functions in digestion, mood and behavior, development and immunity, and a range of acute and chronic diseases. It is therefore critical to understand its evolution and changing ecology through time. Here we review recent findings on the microbiota of diverse human populations, non-human primates, and past human populations and discuss the implications of this research in formulating a deeper evolutionary understanding of the human holobiont.

show abstract

“…69 One of the most reproducible differences between breast and formula-fed infants is that formula fed infants have higher amounts of Clostridium difficile that make up their gut microbiome. 89–92 Some studies also suggest that Bacteroides , Enterococci , and Enterobacteriaceae may be more common in the microbiome of formula fed infants, where staphylococci tend to be more prevalent in breast fed infants (Table 1). 69 When evaluating the impact of breast-feeding on the development of allergic disease, breast-fed infants appear to have a lower rate of early wheezing and asthma, but this affect seems to diminish with age.…”

Section: The Influence Of the Microbiome In Allergic Diseasementioning

confidence: 99%

Gut Microbiome and the Development of Food Allergy and Allergic Disease

Prince

Mandel

Nadeau

et al. 2015

Pediatric Clinics of North America

View full text Add to dashboard Cite

The prevalence of food allergy and other allergic diseases continues to rise within the industrialized world, yet the cause of this epidemic remains elusive. Environmental factors such as microbial exposures have more recently been implicated as one possible driving factor behind the increasing burden of allergic disease. The impact of gut microbiome on human development, nutritional needs, and disease has become evident with advances in our ability to study these complex communities of microorganisms, and there is a growing appreciation for the role of the microbiome in immune regulation. Several studies have examined associations between changes in the commensal microbiota and the development of asthma, allergic rhinitis, and asthma, but far less have evaluated the impact of the microbiome on the development of food allergy. In this article we review the human gastrointestinal microbiome, focusing on the theory and evidence for its role in the development of IgE-mediated food allergy and other allergic diseases.

show abstract

How delivery mode and feeding can shape the bacterial community in the infant gut

Cited by 56 publications

References 7 publications

Gut microbiota: a source of novel tools to reduce the risk of human disease?

Gut microbiota: a source of novel tools to reduce the risk of human disease?

Insights into human evolution from ancient and contemporary microbiome studies

Gut Microbiome and the Development of Food Allergy and Allergic Disease

Contact Info

Product

Resources

About