Introduction: Indonesia is the second highest country of stroke burden after Mongolia, which are 3,382.2 / 100,000 people based on DALYs (disability-adjusted life-year). Based on the health profile of the province of Bali, the type of stroke that has high prevalence rate is ischemic stroke. Practical strategies in overcoming the burden of stroke must be focused on prevention and treatment based on risk factors. The study aims to determine the relationship between risk factors and the level of risk of ischemic stroke patients hospitalized at RSUD Klungkung Bali. Methods: This study is observational analytic study with a cross sectional design that includes 65 patients taken from the medical records. The variables studied are age, gender, pressure blood, cholesterol levels, smoking history, body mass index (BMI), physical activity, history of diabetes, history of atrial fibrillation, and history of stroke in the family. Data analysis techniques used were univariate analysis and bivariate analysis. Result: The most characteristics based on age group is ≥ 55 years-64 years with an average age of 61.45 ± 12.016 years. Patients are dominated by men (2,4:1). The assessment of the level of risk factors in each sample using the Stroke Risk Scorecard (SRS), 51 people (78.5%) had a high risk, 9 people (13.8%) had moderate risk, and 5 people (7.7%) has a low risk of ischemic stroke. Conclusion: The chi-square statistical analysis showed a significant relationship between the risk level of ischemic stroke with body mass index, blood pressure, smoking history, history of diabetes, and cholesterol levels (p<0,005).