2011
DOI: 10.1038/eye.2011.245
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Humphrey visual field findings in hydroxychloroquine toxicity

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Cited by 49 publications
(38 citation statements)
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“…Another study estimated that 10-2 visual field, spectral domain-OCT, and mfERG had high-negative and low-positive predictive values, being able to exclude retinopathy when normal but not able to confirm toxicity if the condition was pathologic 22. Abnormalities in visual field that have been found in patients with hydroxychloroquine-induced retinopathy depend on the test being used, given that central defects are seen in the 24-2 test and paracentral ones in the 10-2 test 30. Frequency-doubling Humphrey perimetry and white-on-white Humphrey visual field perimetry (HVFP) can both be helpful for the diagnosis of retinal abnormalities caused by hydroxychloroquine 31.…”
Section: Discussionmentioning
confidence: 97%
“…Another study estimated that 10-2 visual field, spectral domain-OCT, and mfERG had high-negative and low-positive predictive values, being able to exclude retinopathy when normal but not able to confirm toxicity if the condition was pathologic 22. Abnormalities in visual field that have been found in patients with hydroxychloroquine-induced retinopathy depend on the test being used, given that central defects are seen in the 24-2 test and paracentral ones in the 10-2 test 30. Frequency-doubling Humphrey perimetry and white-on-white Humphrey visual field perimetry (HVFP) can both be helpful for the diagnosis of retinal abnormalities caused by hydroxychloroquine 31.…”
Section: Discussionmentioning
confidence: 97%
“…8 The 10-2 VF test has been highlighted as a key test for detecting the early HCQ toxicity because of its sensitivity in the central macula. 5,9,10 However, very early VF damage may be confused with nonpathologic variations, and some patients do not perform fields reliably. Thus, the American Academy of Ophthalmology guideline emphasized the importance of adding objective testing such as SD OCT and multifocal electroretinography where available.…”
Section: Discussionmentioning
confidence: 98%
“…11 However, the mean deviation value, as an average of the reduction from normal, may also provide useful information regarding overall retinal sensitivity in these patients. Comparisons of 10-2 HVF and microperimetry have received minimal attention in the literature and a direct comparison between these testing methodologies is beyond the scope of this study.…”
Section: Discussionmentioning
confidence: 99%