Hyaluronan alkyl derivatives-based electrospun membranes for potential guided bone regeneration: Fabrication, characterization and in vitro osteoinductive properties

Federico, Salvatore; Pitarresi, Giovanna; Palumbo, Fabio Salvatore; Fiorica, Calogero; Yang, Fang; Giammona, Gaetano

doi:10.1016/j.colsurfb.2020.111438

Cited by 15 publications

(10 citation statements)

References 41 publications

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“…Studies have indicated that HA membrane has an effect close to that of the collagen ( Yilmaz et al, 2021 ). Furthermore, membranes based on HA derivatives hold great potential to stimulate mineralization for the periodontal regeneration ( Federico et al, 2021 ), which can be investigated for periodontal barrier applications and used to achieve bone regeneration ( Park et al, 2009 ). Ayanoğlu et al (2015) conducted a study on the combined use of HA membrane and allograft on bone defects of rabbits.…”

Section: Specific Types Of Barrier Membranesmentioning

confidence: 99%

Advances in Barrier Membranes for Guided Bone Regeneration Techniques

Yang

Shi

et al. 2022

Front. Bioeng. Biotechnol.

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Guided bone regeneration (GBR) is a widely used technique for alveolar bone augmentation. Among all the principal elements, barrier membrane is recognized as the key to the success of GBR. Ideal barrier membrane should have satisfactory biological and mechanical properties. According to their composition, barrier membranes can be divided into polymer membranes and non-polymer membranes. Polymer barrier membranes have become a research hotspot not only because they can control the physical and chemical characteristics of the membranes by regulating the synthesis conditions but also because their prices are relatively low. Still now the bone augment effect of barrier membrane used in clinical practice is more dependent on the body’s own growth potential and the osteogenic effect is difficult to predict. Therefore, scholars have carried out many researches to explore new barrier membranes in order to improve the success rate of bone enhancement. The aim of this study is to collect and compare recent studies on optimizing barrier membranes. The characteristics and research progress of different types of barrier membranes were also discussed in detail.

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Section: Specific Types Of Barrier Membranesmentioning

confidence: 99%

Advances in Barrier Membranes for Guided Bone Regeneration Techniques

Yang

Shi

et al. 2022

Front. Bioeng. Biotechnol.

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“…Federico et al prepared hyaluronic acid with pendant aliphatic tails (HA-C x ) at different lengths, and dexamethasone (Dex)-loaded hyaluronic acid membranes were obtained by electrospinning using polyvinyl alcohol and 2-hydroxypropyl-cyclodextrin as flexible polymeric carriers and rheological modifiers [41] . The aliphatic tails modified the hydrophilicity and degradation of the final membranes and made them suitable for application in the GBR area.…”

Section: Materials To Facilitate Adhesion Migration and Proliferation...mentioning

confidence: 99%

Recent advances in biofunctional guided bone regeneration materials for repairing defective alveolar and maxillofacial bone: A review

Wang

Feng²,

Liu³

et al. 2022

Japanese Dental Science Review

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“…Finally, the possibility of using injectable systems for the delivery of two bioactive molecules widely used in bone tissue engineering such as Dexamethasone and stromal cell‐derived factor‐1 (SDF‐1) was investigated. In particular, Dexamethasone is a synthetic glucocorticoid with known osteoinductive effects on mesenchymal stem cell differentiation, [ 28,29 ] while SDF‐1 is a potent chemokine, which stimulates the recruitment of stem cells in both normal and damaged tissues interacting with the CXC type‐4 chemokine receptor (CXCR4) stimulating cell migration and accelerating regeneration. [ 30,31 ]…”

Section: Introductionmentioning

confidence: 99%

Composite Hydrogels of Alkyl Functionalized Gellan Gum Derivative and Hydroxyapatite/Tricalcium Phosphate Nanoparticles as Injectable Scaffolds for bone Regeneration

Pitarresi

Palumbo

Fiorica

et al. 2021

Macromolecular Bioscience

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An alkyl functionalized gellan gum derivative is here used to produce hydrogels containing hydroxyapatite and tricalcium phosphate nanoparticles as injectable nanostructured scaffolds for bone regeneration. The amphiphilic nature of the polysaccharide derivative along with its thermotropic behavior and ionotropic crosslinking features make possible to produce injectable bone mimetic scaffolds that can be used to release viable cells and osteoinductive biomolecules. The influence of different nanoparticles concentration on the rheological and physicochemical properties of the injectable systems is studied. It is found that the presence of inorganic nanoparticles reinforces the 3D hydrated polymeric networks without influencing their injectability but improving the physicochemical properties of ionotropic crosslinked hydrogels produced with two different curing media. Preliminary cytocompatibility tests performed with murine preosteoblast cells revealed that gellan gum based hydrogels can safely encapsulate viable cells. Loading and release experiments for dexamethasone and stromal cell‐derived factor‐1 demonstrate the drug delivery features of the obtained injectable systems.

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Hyaluronan alkyl derivatives-based electrospun membranes for potential guided bone regeneration: Fabrication, characterization and in vitro osteoinductive properties

Cited by 15 publications

References 41 publications

Advances in Barrier Membranes for Guided Bone Regeneration Techniques

Advances in Barrier Membranes for Guided Bone Regeneration Techniques

Recent advances in biofunctional guided bone regeneration materials for repairing defective alveolar and maxillofacial bone: A review

Composite Hydrogels of Alkyl Functionalized Gellan Gum Derivative and Hydroxyapatite/Tricalcium Phosphate Nanoparticles as Injectable Scaffolds for bone Regeneration

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