Hybrid silica-coated Gd-Zn-Cu-In-S/ZnS bimodal quantum dots as an epithelial cell adhesion molecule targeted drug delivery and imaging system

Akbarzadeh, Marzieh; Babaei, Maryam; Abnous, Khalil; Taghdisi, Seyed Mohammad; Peivandi, Mohammad Taghi; Ramezani, Mohammad; Alibolandi, Mona

doi:10.1016/j.ijpharm.2019.118645

Cited by 45 publications

(21 citation statements)

References 46 publications

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“…Following the same track, various researchers in recent time have explored more water soluble drugs that were successfully immobilized onto the silica nanoparticles and used for drug delivery [103][104][105][106][107]. For example, Marzieh et al [108] developed silica based nanocarriers for the target delivery of doxorubicin drug to breast cancer cells (4T1). The nanocarriers were fabricated with quantum dots (QD) coating on MSNs followed by amine functionalization of silica surface.…”

Section: Biomedical and Biotechnological Applications Of Snpsmentioning

confidence: 99%

“…Open Access ref. [108] loaded MSNs with genetic material and chemical inducer to be successfully carried into intact leaves and plant cells of maize seeds. This pre-treatment of maize seeds with silica nanoparticles resulted in maize seeds with antifungal resistance, higher nutritional content and greater germination rate.…”

Section: Agricultural Applications Of Snpsmentioning

confidence: 99%

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A Comprehensive Review of Synthesis, Applications and Future Prospects for Silica Nanoparticles (SNPs)

Akhter

Rao

Abbasi

et al. 2022

Silicon

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Silica nanoparticles (SNPs) have shown great applicability potential in a number of fields like chemical, biomedical, biotechnology, agriculture, environmental remediation and even wastewater purification. With remarkably instinctive properties like mesoporous structure, high surface area, tunable pore size/diameter, biocompatibility, modifiability and polymeric hybridizability, the SNPs are growing in their applicable potential even further. These particles are shown to be non-toxic in nature, hence safe to be used in biomedical research. Moreover, the molecular mobilizability onto the internal and external surface of the particles makes them excellent carriers for biotic and non-biotic compounds. In this respect, the present study comprehensively reviews the most important and recent applications of SNPs in a number of fields along with synthetic approaches. Moreover, despite versatile contributions, the applicable potential of SNPs is still a tip of the iceberg waiting to be exploited more, hence, the last section of the review presents the future prospects containing only few of the many gaps/research extensions regarding SNPs that need to be addressed in future work.

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Section: Biomedical and Biotechnological Applications Of Snpsmentioning

confidence: 99%

Section: Agricultural Applications Of Snpsmentioning

confidence: 99%

A Comprehensive Review of Synthesis, Applications and Future Prospects for Silica Nanoparticles (SNPs)

Akhter

Rao

Abbasi

et al. 2022

Silicon

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“…Silica-coated bipolar quantum dots were investigated by Akbarzadeh et al They reported that the synthesis of intelligent nano-aptamer was targeted by QDs coated with porous meso silica with a bimodal imaging capacity. Their results showed that the targeted hybrid system that was prepared based on their in-vivo test has MR capability and fluorescent imaging [ 237 ]. Iannazzoa et al examined the use of graphene QDs in cancer treatment and drug delivery.…”

Section: Biomedical Applicationsmentioning

confidence: 99%

Bioactive Graphene Quantum Dots Based Polymer Composite for Biomedical Applications

et al. 2022

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Today, nanomedicine seeks to develop new polymer composites to overcome current problems in diagnosing and treating common diseases, especially cancer. To achieve this goal, research on polymer composites has expanded so that, in recent years, interdisciplinary collaborations between scientists have been expanding day by day. The synthesis and applications of bioactive GQD-based polymer composites have been investigated in medicine and biomedicine. Bioactive GQD-based polymer composites have a special role as drug delivery carriers. Bioactive GQDs are one of the newcomers to the list of carbon-based nanomaterials. In addition, the antibacterial and anti-diabetic potentials of bioactive GQDs are already known. Due to their highly specific surface properties, π-π aggregation, and hydrophobic interactions, bioactive GQD-based polymer composites have a high drug loading capacity, and, in case of proper correction, can be used as an excellent option for the release of anticancer drugs, gene carriers, biosensors, bioimaging, antibacterial applications, cell culture, and tissue engineering. In this paper, we summarize recent advances in using bioactive GQD-based polymer composites in drug delivery, gene delivery, thermal therapy, thermodynamic therapy, bioimaging, tissue engineering, bioactive GQD synthesis, and GQD green resuscitation, in addition to examining GQD-based polymer composites.

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“…Akbarzadeha et al [115] studied the silica-coated dipole quantum dots. They reported the synthesis of smart nano aptamer-targeted by mesoporous silica-coated QDs having bimodal imaging capacity.…”

Section: Drug Deliverymentioning

confidence: 99%

A Review of Clinical Applications of Graphene Quantum Dot-based Composites

Asadi

Chimeh

Hosseini

et al. 2019

jcc

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This review represents an overview of the graphene quantum dots (GQDs) synthesis and their applications as carriers or probes for the sensor, imaging, drug delivery, and diagnosing of diseases. Furthermore, recent developments in the GQDs for therapy and their potential toxicity for both in vitro and in vivo are reviewed. The recent findings and issues for GQDs and their composites with respect to stability and optimal size and toxicity at various applications are presented.

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Hybrid silica-coated Gd-Zn-Cu-In-S/ZnS bimodal quantum dots as an epithelial cell adhesion molecule targeted drug delivery and imaging system

Cited by 45 publications

References 46 publications

A Comprehensive Review of Synthesis, Applications and Future Prospects for Silica Nanoparticles (SNPs)

A Comprehensive Review of Synthesis, Applications and Future Prospects for Silica Nanoparticles (SNPs)

Bioactive Graphene Quantum Dots Based Polymer Composite for Biomedical Applications

A Review of Clinical Applications of Graphene Quantum Dot-based Composites

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