Hydrogel-mediated drug delivery for treating stroke

Energy‐Dissipative Hydrogels: A Promising Material for Tissue Regeneration†

“…dynamic host‐guest hydrogels crosslinked via CB[7] host and hexanoate‐isoquinoline (HIQ) guest and the energy dissipation could be tuned by changing the pH or treating the network with CO 2 and NH 3 (Figure 7). [ 39 ]…”

“…Energy‐dissipative hydrogels based on cucurbit[ n ]urils. (a) Schematic illustration of energy‐dissipative hydrogels crosslinked CB[7] host and hexanoate‐isoquinoline (HIQ) guest. (b) (c) Effects of PH on energy dissipation.…”

“…[ 6 ] Hydrogel, a type of materials that have the potential to mimic ECM, composed of hydrophilic polymer networks that can swell in and hold a large amount of aqueous solution, has been widely investigated. [ 7‐8 ] Owing to their outstanding resemblance to tissue, remarkable and unique properties including tunable physical and biochemical properties, high biocompatibility, and versatility in fabrication, hydrogels play an increasingly important role in regenerative medicine and tissue engineering. [ 9‐14 ] However, as traditional hydrogels are composed of covalently crosslinked networks, they are purely elastic and prone to permanent breakage, which limits their scope of application.…”

Investigation of synergic effects of nanogroove topography and polyaniline-chitosan nanocomposites on PC12 cell differentiation and axonogenesis

“…This implant can initiate neurogenesis by suppressing inflammation with amino acids as crosslinks. 16 Electroconductive materials such as polyaniline (PANI), polypyrrole (PPy), poly (3,4- ethylenedioxythiophene) (PEDOT), and graphite derivatives such as graphene oxide (GO) and graphene quantum dots (GQDs) work as the best candidates for studying cellular behavior in neurons. 15 , 17 , 18 , 19 As a result of its biocompatibility and low cytotoxicity, PANI appears to be a suitable electroconductive material for studying neuronal behaviors in both single-cell and tissue stages.…”

Hydrogel-Based Stimuli-Responsive Radiative and/or Evaporative Cooling Materials for Carbon Neutrality

“…Hydrogels are networks of cross-linked or hydrogen-bonded polymers that can be swollen by large amounts of water due to the presence of hydrophilic molecules in their chemical structure. , In recent years, hydrogels have been explored for various applications such as drug release textiles, drug delivery, , temperature sensors, , smart windows, − and many other fields. , In addition to the appealing properties that are employed in these broad application areas, hydrogel can offer an additional merit which is effective radiative and/or evaporative cooling.…”