Hydrogen‐Bonded Supramolecular Assemblies as Robust Templates in the Synthesis of Large Metal‐Coordinated Capsules

Abstract

Uncommon water chain: A large neutral hexameric coordination cage [Ga12(H2O)24(C40H42O12)6⊂(acetone)8(H2O)6] is assembled from six pyrogallol[4]arene ligands and twelve GaIII ions. Found within the capsule structure are two pseudo‐linear hydrogen‐bonded water (H2O)5 chains (see picture, Ga gold, O red).

Metallo-supramolecular capsules

“…From the work reviewed in this article, we have also shown that they are also useful templates for metal-organic analogues [116,[118][119][120][121]124,127]. The remarkable replacement of 48 hydrogen atoms in the hydrogen-bonded 'seam' with 24 copper Fig.…”

“…By exchanging copper(II) nitrate for gallium(III) nitrate in an acetone/water solvent system containing PgC 3 , diffraction quality colourless single crystals form over a number of hours [119]. Structural analysis of this material afforded a metal-organic capsule composed of six PgC 3 molecules and 12 gallium centres that has a distorted 'rugby-ball' like shape which is markedly different to the spherical type nano-capsules described in Section 3.1 (Fig.…”

“…When considering some of the largest supramolecular container assemblies formed to date [16,19,23,[47][48][49][50][68][69][70][84][85][86], hydrogen-bonded pyrogallol- [4]arene capsules (either dimeric or hexameric) are useful for the encapsulation of reasonably large non-solvent molecules, as identified by X-ray diffraction studies [96][97][98][99][100][101][102][103]116,[118][119][120]. From the work reviewed in this article, we have also shown that they are also useful templates for metal-organic analogues [116,[118][119][120][121]124,127].…”

A Ga3+self-assembled fluorescent probe for ATP imaging in vivo

“…S4). Together with these, one of possible multi-membered arrays assembled between DHBO and Ga 3 þ ions was illustrated in Scheme 1, where Ga 3 þ functions as quadridentate ligand like literature reported (McKinlay et al, 2005).…”

“…The turn-on fluorescence signal can effectively discriminate ATP from ADP and adenosine 5′-monophosphate (AMP). Ga 3 þ ions were found to easily coordinate with oxygen atoms of hydroxyphenyl segments (Hastings et al, 2014;McKinlay et al, 2005McKinlay et al, , 2006. DHBO ligand is a typical fluorophore known for its excited state intramolecular proton transfer (ESIPT) characteristic (Xu et al, 2014).…”