Hydroxyapatite/gelatin functionalized graphene oxide composite coatings deposited on TiO2 nanotube by electrochemical deposition for biomedical applications

Yan, Yajing; Zhang, Xuejiao; Mao, Huanhuan; Huang, Yong; Ding, Qiongqiong; Pang, Xin

doi:10.1016/j.apsusc.2014.12.115

Cited by 74 publications

(29 citation statements)

References 43 publications

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“…Most recently, Loget et al [127] coated biomimetic polydopamine into TNT for the development of biomedical devices. Similarly, graphene oxide coating has been done on TNT for biomedical applications [128]. The TNT can be used as a field emission electron source for generating X-ray radiation.…”

Section: Doping Of Tnt With Other Elementsmentioning

confidence: 99%

A Review on TiO2 Nanotubes: Influence of Anodization Parameters, Formation Mechanism, Properties, Corrosion Behavior, and Biomedical Applications

et al. 2015

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In this article, influence of anodization parameters on the formation of tubes, tube dimensions, formation mechanism, properties of TiO 2 nanotubes (TNT), and their applications in biomedical field are reviewed. The fabrication of TNT of a different shape such as pore size, length, and wall thickness by varying anodization parameters including electrolytes, pH, voltage, electrolyte bath temperature, and current density is examined and discussed. The crystallographic nature of the nanotube obtained by various methods has also been discussed. Finally, the article concludes by examining the key properties including the corrosion aspect and various applications in biomedical field in depth.

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Section: Doping Of Tnt With Other Elementsmentioning

confidence: 99%

A Review on TiO2 Nanotubes: Influence of Anodization Parameters, Formation Mechanism, Properties, Corrosion Behavior, and Biomedical Applications

et al. 2015

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“…A graphene‐reinforced calcium silicate coating had good mechanical properties, and in vivo experiments demonstrated compatibility and integration with host bone . Additionally, a GO cross‐linked gelatin reinforced HA coating on TiO 2 nanotube arrays had good mechanical properties and corrosion resistance, having potential for biomedical applications …”

Section: Go As a Scaffold For Bone Regenerationmentioning

confidence: 99%

Graphene oxide as a scaffold for bone regeneration

Holt

Wright

Arnold

et al. 2016

WIREs Nanomed Nanobiotechnol

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Graphene oxide (GO), the oxidized form of graphene, holds great potential as a component of biomedical devices, deriving utility from its ability to support a broad range of chemical functionalities and its exceptional mechanical, electronic, and thermal properties. GO composites can be tuned chemically to be biomimetic, and mechanically to be stiff yet strong. These unique properties make GO-based materials promising candidates as a scaffold for bone regeneration. However, questions still exist as to the compatibility and long-term toxicity of nanocarbon materials. Unlike other nanocarbons, GO is meta-stable, water dispersible, and autodegrades in water on the timescale of months to humic acid-like materials, the degradation products of all organic matter. Thus, GO offers better prospects for biological compatibility over other nanocarbons. Recently, many publications have demonstrated enhanced osteogenic performance of GO-containing composites. Ongoing work toward surface modification or coating strategies could be useful to minimize the inflammatory response and improve compatibility of GO as a component of medical devices. Furthermore, biomimetic modifications could offer mechanical and chemical environments that encourage osteogenesis. So long as care is given to assure their safety, GO-based materials may be poised to become the next generation scaffold for bone regeneration. WIREs Nanomed Nanobiotechnol 2017, 9:e1437. doi: 10.1002/wnan.1437 For further resources related to this article, please visit the WIREs website.

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“…It may be due to the unique physicochemical performance of Ag nanoparticles and GO. 18 In fact, the mechanisms of S. aureus and E. coli were different as well. The nanocomposite played a bactericidal role against S. aureus by significantly inhibiting bacterial division; while it was against E. coli by destroying the integrity of bacterial cell wall.…”

Section: Introductionmentioning

confidence: 99%

“…The nanocomposite played a bactericidal role against S. aureus by significantly inhibiting bacterial division; while it was against E. coli by destroying the integrity of bacterial cell wall. 18 In recent years, GO, being rich in oxygen-containing functional groups, has attracted increasing attentions in biomedicine for its wide applications, such as gene transfection, photothermal therapy, tumor imaging, biosensing, as well as drug delivery due to their outstanding optical, physicochemical and mechanical properties. 19 On the one hand, it is reported that GO can promote cell adhesion, proliferation, and differentiation trough electrostatic and hydrophobic interactions.…”

Section: Introductionmentioning

confidence: 99%

<p>Functionalized titanium implant in regulating bacteria and cell response</p>

Jin¹,

Fei²,

Zhang³

et al. 2019

IJN

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Background: Biological complications are an issue of critical interest in contemporary dental and orthopedic fields. Although titanium (Ti), graphene oxide (GO) or silver (Ag) particles are suitable for biomedical implants due to their excellent cytocompatibility, bioactivity, and antibacterial properties, the exact antibacterial mechanism is not understood when the three substances are combined (Ti-GO-Ag). Materials and methods: In this work, the material characterization, antibacterial property, antibacterial mechanisms, and cell behavior of Ti-GO-Ag fabricated by electroplating and ultraviolet reduction methods respectively, were investigated in detail. Results:The material char acterization of Ti-GO-Ag tested by atomic force microscopy, Raman spectroscopy, X-ray photoelectron spectroscopy, nanoindentation, nanoscratch, inductively coupled plasma mass spectrometer, and contact angle tester revealed the importance of GO concentration and Ag content in the preparation process. The antibacterial tests of Ti-GO-Ag clearly demonstrated the whole process of bacteria interacting with materials, including reactive oxygen species, endocytosis, aggregation, perforation, and leakage. In addition, the behavior of Ti-GO-Ag showed that cell area, length, width, and fluorescence intensity were affected. Conclusion: Briefly, Ti-GO-Ag nanocomposite was a dual-functionalized implant biomaterial with antibacterial and biocom patible characterization.

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Hydroxyapatite/gelatin functionalized graphene oxide composite coatings deposited on TiO2 nanotube by electrochemical deposition for biomedical applications

Cited by 74 publications

References 43 publications

A Review on TiO2 Nanotubes: Influence of Anodization Parameters, Formation Mechanism, Properties, Corrosion Behavior, and Biomedical Applications

A Review on TiO2 Nanotubes: Influence of Anodization Parameters, Formation Mechanism, Properties, Corrosion Behavior, and Biomedical Applications

Graphene oxide as a scaffold for bone regeneration

<p>Functionalized titanium implant in regulating bacteria and cell response</p>

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