Hyoid Bone Metastasis in Patients With Lung Adenocarcinoma: A Case Report

Abstract

Objective: Hyoid bone metastasis from lung adenocarcinoma is exceedingly rare. This study aims to provide an experience to clinicians in the differential diagnosis of hyoid tumors and discusses its possible source. Methods and Results: We report a 68-year-old male patient having hyoid bone metastasis from lung adenocarcinoma. The initial symptom of the hyoid bone metastasis was neck pain exacerbated by swallowing. The hyoid bone mass was resected based on comprehensive analysis including whole-body bone imaging and pathologic analysis of the hyoid bone mass. The adenocarcinoma of hyoid was identified as a metastatic lesion of lung adenocarcinoma. The patient recovered well and the anterior cervical pain was significantly alleviated after surgery and the patient underwent corresponding chemotherapy. Conclusion: In patients with hyoid metastasis of lung adenocarcinoma, surgical resection may reduce the pain in anterior cervical after full consideration of physical condition.

Radiotherapy for hyoid bone metastasis from lung adenocarcinoma: A case report

“…The previously documented patient elected for surgical resection of the hyoid bone[ 1 ]. Our patient opted out of surgery, due to its significant risks which could negatively impact her quality of life.…”

“…This case report accounts for the second reported instance of hyoid metastasis from lung adenocarcinoma. Metastatic tumors to the hyoid bone are rare, with sporadic instances reported in breast, liver, colon, skin, lung, and prostate cancers[ 1 - 6 ]. We present the case of a 72-year-old female patient with stage IV terminal lung cancer presenting with throat pain attributed to a metastatic tumor on the hyoid.…”

Melanoma metastatic to the hyoid bone

“…1 Only a few cases of tumors metastatic to the hyoid bone have been reported in the literature, including carcinomas originating in breast, kidney, liver, colon, and lung. 1 Cutaneous melanoma is a malignant tumor originating from melanocytes and is the 5th most common cancer in men and 6th most common in women in the United States. 2 Bone metastases from melanoma are relatively common, observed in 11%-17% of melanoma patients clinically and in 23%-49% of melanoma patients in autopsy studies.…”

“…Malignant tumors of the hyoid bone are rare and include sarcomas, plasmacytomas, and distant metastases. 1 Only a few cases of tumors metastatic to the hyoid bone have been reported in the literature, including carcinomas originating in breast, kidney, liver, colon, and lung. 1 Cutaneous melanoma is a malignant tumor originating from melanocytes and is the 5th most common cancer in men and 6th most common in women in the United States.…”

“…Malignant tumors of the hyoid bone are rare and include sarcomas, plasmacytomas, and distant metastases 1 . Only a few cases of tumors metastatic to the hyoid bone have been reported in the literature, including carcinomas originating in breast, kidney, liver, colon, and lung 1 …”