Hyperkinesis: pathogenesis, clinical features, diagnosis, treatment (clinical lecture)

Abstract

Traditionally, the basic etiological concepts are considered in the views on the morphophysiological basis of hyperkinesis. Hyperkinesia is associated with hypotonia, a decrease in muscle tone, and hyperkinetic disorders are psychogenic and manifest in childhood. Hyperkinesia can be caused by a large number of various diseases, including metabolic disorders, endocrine disruption, hereditary disorders, vascular disorders or traumatic disorders. Other causes include intoxication of the nervous system, autoimmune diseases and infections. The classification of hyperkinesis is that hyperkinetic motions can be defined as any undesirable, excessive movements that can be distinguished from each other, based on the degree to which they are rhythmic, discrete, repetitive and random. When assessing a patient with suspected hyperkinesia, the doctor thoroughly records in the history of the disease a clear description of the movements, the medications prescribed in the past and present, the family history of the similar diseases, the history of the disease, including past infections, and any other influences. Treatment is aimed at reducing symptoms, restoring normal posture and improving the general condition of the patient.

Wireless EEG Recording of Audiogenic Seizure Activity in Freely Moving Krushinsky-Molodkina Rats

“…In particular, the path of seizure propagation remains consistent between episodes. Hyperkinesis can also be induced through a regimen of interrupted phonostimulations, thereby offering the animals an additional 15 minutes for recovery after exiting the cataleptoid state [26]. This methodology seems to increase the convulsive readiness of specific brain regions, thus enhancing the intensity of seizures in some animals [27].…”